TNK1 Antikörper (AA 451-560)
(2 Referenzen)-
- Target Alle TNK1 Antikörper anzeigen
- TNK1 (Tyrosine Kinase, Non-Receptor, 1 (TNK1))
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Bindungsspezifität
- AA 451-560
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser TNK1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of TNK1 (aa451-560) expressed in E. coli.
- Klon
- 1B5G3
- Isotyp
- IgG1
- Top Product
- Discover our top product TNK1 Primärantikörper
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anti-Tyrosine Kinase, Non-Receptor, 1 (TNK1) (AA 256-286) antibody
TNK1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB3104 unconjugated
anti-Tyrosine Kinase, Non-Receptor, 1 (TNK1) antibodyTNK1 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Tyrosine Kinase, Non-Receptor, 1 (TNK1) (AA 256-286) antibodyTNK1 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Tyrosine Kinase, Non-Receptor, 1 (TNK1) (AA 554-588), (C-Term) antibodyTNK1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB50687 unconjugated
anti-Tyrosine Kinase, Non-Receptor, 1 (TNK1) (pTyr277) antibodyTNK1 Reaktivität: Maus WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Tyrosine Kinase, Non-Receptor, 1 (TNK1) (AA 517-566) antibodyTNK1 Reaktivität: Human WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Tyrosine Kinase, Non-Receptor, 1 (TNK1) antibodyTNK1 Reaktivität: Maus WB, ELISA Wirt: Maus Monoclonal 170CT7-5-4 unconjugated
anti-Tyrosine Kinase, Non-Receptor, 1 (TNK1) (Middle Region) antibodyTNK1 Reaktivität: Human WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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: "Thirty-eight-negative kinase 1 (TNK1) facilitates TNFalpha-induced apoptosis by blocking NF-kappaB activation." in: Oncogene, Vol. 26, Issue 45, pp. 6536-45, (2007) (PubMed).
: "Kos1, a nonreceptor tyrosine kinase that suppresses Ras signaling." in: Oncogene, Vol. 22, Issue 23, pp. 3562-77, (2003) (PubMed).
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: "Thirty-eight-negative kinase 1 (TNK1) facilitates TNFalpha-induced apoptosis by blocking NF-kappaB activation." in: Oncogene, Vol. 26, Issue 45, pp. 6536-45, (2007) (PubMed).
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- Target
- TNK1 (Tyrosine Kinase, Non-Receptor, 1 (TNK1))
- Andere Bezeichnung
- TNK1 (TNK1 Produkte)
- Synonyme
- Kos1 antikoerper, Tnk1a antikoerper, Tnk1b antikoerper, Ack-like antikoerper, tyrosine kinase non receptor 1 antikoerper, tyrosine kinase, non-receptor, 1 antikoerper, TNK1 antikoerper, Tnk1 antikoerper
- Hintergrund
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Description: TNK1: tyrosine kinase, non-receptor, 1. TNK1 is a nonreceptor tyrosine kinase(NRPTK). These kinases, like members of the SRC (MIM 190090) and JAK (see MIM 147795) families, mediate intracellular signaling downstream of receptor activation.Tnk1 is a ubiquitously expressed 47- kDa protein with autotyrosine kinase activity that is developmentally regulated during embryogenesis. Tnk1 is also upregulated following IL3 withdrawal from factor-dependent murine NSF/N1.H7 cells that undergo apoptosis, suggesting a role in growth inhibition. Data support a negative regulatory role for Tnk1 in regulating the Ras-Raf1-MAPK growth pathway by a mechanism that requires its autotyrosine kinase activity.
Aliases: MGC46193, TNK1
- Gen-ID
- 8711
- HGNC
- 8711
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