EPH Receptor B4 Antikörper (AA 562-612)

Produktnummer ABIN1724713

Produktdetails anti-EPH Receptor B4 Antikörper

Target: EPH Receptor B4 (EPHB4)

Bindungsspezifität: AA 562-612

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser EPH Receptor B4 Antikörper ist unkonjugiert

Applikation: ELISA

Verwendungszweck: EphB4 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of EphB4 (aa562-612)expressed in E. Coli.

Klon: 7H4A6

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-EPH Receptor B4 Antikörper (ABIN1724713)

Red-Horse, Kapidzic, Zhou, Feng, Singh, Fisher: "EPHB4 regulates chemokine-evoked trophoblast responses: a mechanism for incorporating the human placenta into the maternal circulation." in: Development (Cambridge, England), Vol. 132, Issue 18, pp. 4097-106, (2005) (PubMed).

Xia, Kumar, Masood, Zhu, Reddy, Krasnoperov, Quinn, Henshall, Sutherland, Pinski, Daneshmand, Buscarini, Stein, Zhong, Broek, Roy-Burman, Gill: "EphB4 expression and biological significance in prostate cancer." in: Cancer research, Vol. 65, Issue 11, pp. 4623-32, (2005) (PubMed).

Jiménez-Vega, Yepiz-Plascencia, Söderhäll, Vargas-Albores: "A single WAP domain-containing protein from Litopenaeus vannamei hemocytes." in: Biochemical and biophysical research communications, Vol. 314, Issue 3, pp. 681-7, (2004) (PubMed).

Details zu EPH Receptor B4

Target: EPH Receptor B4 (EPHB4)

Andere Bezeichnung: EphB4 (EPHB4 Produkte)

Hintergrund:

Description: EphB4: EPH receptor B4. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.

Aliases: HTK, MYK1, TYRO11

Molekulargewicht: 108kDa

Gen-ID: 2050

HGNC: 2050

UniProt: P54760

Pathways: RTK Signalweg