HSC70 Interacting Protein HIP Antikörper

Produktnummer ABIN1724716

Dieses Maus Monoklonal-Antikörper erkennt spezifisch HSC70 Interacting Protein HIP in WB, ELISA, IHC und ICC. Er zeigt eine Reaktivität gegenüber Human und Affe und wurde in 1 Publikation erwähnt.

Kurzübersicht für HSC70 Interacting Protein HIP Antikörper (ABIN1724716)

Target: HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))

Reaktivität: Human, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HSC70 Interacting Protein HIP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Klon: 3B10

Produktdetails anti-HSC70 Interacting Protein HIP Antikörper

Verwendungszweck: ST13 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human ST13 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-HSC70 Interacting Protein HIP Antikörper (ABIN1724716)

Zhou, Lucas, Chan, Issaq, Petricoin, Liotta, Veenstra, Conrads: "An investigation into the human serum "interactome"." in: Electrophoresis, Vol. 25, Issue 9, pp. 1289-98, (2004) (PubMed).

Details zu HSC70 Interacting Protein HIP

Target: HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))

Andere Bezeichnung: ST13

Hintergrund: ST13 (suppression of tumorigenicity protein 13), also known as Hip (HSP70-interacting protein), is one of several co-chaperones that regulate activities of the HSP70 chaperone family. The homo-oligomeric protein Hip cooperates with HSP70 in protein folding by stabilizing the ADP-bound state of HSP70. Hip directly binds to the ATPase domain of HSP70 when it is converted to the ADP-bound state by proteins of the HSP40 family. By collaborating with other positive co-factors such as HSP40 and Hop, or competing with negative co-factors such as Bag1, Hip may facilitate the chaperone function of HSP70 in protein folding and repair, and in controlling the activity of regulatory proteins such as steroid receptors and various regulators of proliferation or apoptosis.

Molekulargewicht: 48 kDa

Gen-ID: 6767

UniProt: P50502