PARP1 Antikörper
(1 reference)-
- Target Alle PARP1 Antikörper anzeigen
- PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser PARP1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Verwendungszweck
- PARP Antibody
- Aufreinigung
- Ascitic fluid
- Immunogen
- Synthetic peptide of human PARP, conjugated to KLH.
- Klon
- 7A10
- Isotyp
- IgG1
- Top Product
- Discover our top product PARP1 Primärantikörper
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anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) antibody
KO Validated PARP1 Reaktivität: Human WB, IP, IF, IHC (p), ICC, ChIP Wirt: Kaninchen Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 81-390) antibodyPARP1 Reaktivität: Human WB, IHC, IP, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 661-881) antibodyPARP1 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 201-300) antibodyPARP1 Reaktivität: Human, Maus, Ratte, Huhn WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (C-Term) antibodyPARP1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 1-100) antibodyPARP1 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 3G4 unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 670-858) antibodyPARP1 Reaktivität: Human, Maus, Ratte WB, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) antibodyPARP1 Reaktivität: Human WB, ELISA, IHC, FACS, IF Wirt: Kaninchen Monoclonal 8C7 unconjugated Recombinant Antibody
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (cleaved) antibodyPARP1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 183-214) antibodyPARP1 Reaktivität: Human WB, ELISA, FACS, IF Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "The enzymatic and DNA binding activity of PARP-1 are not required for NF-kappa B coactivator function." in: The Journal of biological chemistry, Vol. 276, Issue 49, pp. 45588-97, (2001) (PubMed).
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: "The enzymatic and DNA binding activity of PARP-1 are not required for NF-kappa B coactivator function." in: The Journal of biological chemistry, Vol. 276, Issue 49, pp. 45588-97, (2001) (PubMed).
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- Target
- PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
- Andere Bezeichnung
- PARP (PARP1 Produkte)
- Hintergrund
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Description: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Aliases: PARP, PPOL, ADPRT, ADPRT1, PARP-1, pADPRT-1, PARP1
- Molekulargewicht
- 117kDa
- Gen-ID
- 142
- HGNC
- 142
- UniProt
- P09874
- Pathways
- Apoptose, Caspase Kaskade in der Apoptose, DNA Reparatur, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
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