RUNX3 Antikörper (AA 186-252)

Produktnummer ABIN1724742

Produktdetails anti-RUNX3 Antikörper

Target: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Bindungsspezifität: AA 186-252

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RUNX3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Verwendungszweck: RUNX3 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human RUNX3 (AA:186-252) expressed in E. Coli.

Klon: 2B3

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-RUNX3 Antikörper (ABIN1724742)

Mei, Bai, Liu, Li, Wu, Yu, Zheng: "RUNX3 expression is lost in glioma and its restoration causes drastic suppression of tumor invasion and migration." in: Journal of cancer research and clinical oncology, Vol. 137, Issue 12, pp. 1823-30, (2011) (PubMed).

Details zu RUNX3

Target: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Andere Bezeichnung: RUNX3 (RUNX3 Produkte)

Synonyme: runxb antikoerper, RUNX3 antikoerper, CBFA3 antikoerper, frrunx3 antikoerper, runx3 antikoerper, aml2 antikoerper, cbfa3 antikoerper, pebp2ac antikoerper, AML2 antikoerper, Cbfa3 antikoerper, Pebp2a3 antikoerper, PEBP2aC antikoerper, runt-related transcription factor 3 antikoerper, runt related transcription factor 3 antikoerper, runt related transcription factor 3 L homeolog antikoerper, runx3 antikoerper, RUNX3 antikoerper, runx3.L antikoerper, Runx3 antikoerper

Hintergrund:

Description: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Aliases: AML2, CBFA3, PEBP2aC, FLJ34510, MGC16070

Molekulargewicht: 44.4kDa

Gen-ID: 864

HGNC: 864

UniProt: Q13761