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Chromogranin A Antikörper (AA 87-252)

Name: Chromogranin A Antikörper (AA 87-252)
Brand: antibodies-online
SKU: ABIN1724755
Price: 614.71 EUR
Availability: InStock

CHGA Reaktivität: Human FACS, WB, ELISA, ICC Wirt: Maus Monoclonal 1A6B6 unconjugated

Western blot analysis using CHGA mouse mAb against MOLT4 (1), SK-N-SH (2), HepG2 (3), and PC-12 (4) cell lysate. (Chromogranin A Antikörper (AA 87-252))

Western blot analysis using CHGA mAb against human CHGA recombinant protein. (Chromogranin A Antikörper (AA 87-252))

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (Chromogranin A Antikörper (AA 87-252))

ELISA

Flow cytometric analysis of HeLa cells using CHGA mouse mAb (green) and negative control (purple). (Chromogranin A Antikörper (AA 87-252))

FACS

Immunofluorescence analysis of HepG2 cells using CHGA mouse mAb (green). (Chromogranin A Antikörper (AA 87-252))

5 Abbildungen

(2 Referenzen)

Produktnummer ABIN1724755

Datenblatt (PDF)

Target Alle Chromogranin A (CHGA) Antikörper anzeigen

Chromogranin A (CHGA)
Bindungsspezifität
21

15

7

7

5

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 87-252
Reaktivität
207

76

66

29

28

15

6

5

4

3

2

2

1

1
Human
Wirt
118

97

5

1
Maus
Passende Sekundärantikörper
Klonalität
123

97
Monoklonal
Konjugat
95

17

11

10

10

10

10

10

7

5

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Dieser Chromogranin A Antikörper ist unkonjugiert
Applikation
110

106

77

68

60

50

30

14

13

11

10

5

4

3

3

1

1

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Verwendungszweck

CHGA Antibody

Aufreinigung

Ascitic fluid

Immunogen

Purified recombinant fragment of human CHGA (AA: 87-252 ) expressed in E. Coli.

Klon

1A6B6

Isotyp

IgG1

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Applikationshinweise

ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Mergler, Skrzypski, Sassek, Pietrzak, Pucci, Wiedenmann, Strowski: "Thermo-sensitive transient receptor potential vanilloid channel-1 regulates intracellular calcium and triggers chromogranin A secretion in pancreatic neuroendocrine BON-1 tumor cells." in: Cellular signalling, Vol. 24, Issue 1, pp. 233-46, (2011) (PubMed).

El Ali, Fichna, Piniewska, Kosowicz, Grzymis?awski: "Chromogranin A as a useful neuroendocrine marker in patients with autoimmune Addison's disease." in: Journal of endocrinological investigation, Vol. 33, Issue 3, pp. 186-91, (2010) (PubMed).
Target

Chromogranin A (CHGA)

Andere Bezeichnung

CHGA (CHGA Produkte)

Synonyme

CGA antikoerper, CG-ALPHA antikoerper, FSHA antikoerper, GPHA1 antikoerper, GPHa antikoerper, HCG antikoerper, LHA antikoerper, TSHA antikoerper, ChrA antikoerper, fj05f09 antikoerper, si:dkey-177p2.2 antikoerper, wu:fj05f09 antikoerper, zgc:101749 antikoerper, zgc:56075 antikoerper, CHGA antikoerper, cgA antikoerper, chga antikoerper, chromogranin A antikoerper, glycoprotein hormones, alpha polypeptide antikoerper, uncharacterized CHGA antikoerper, chromogranin A S homeolog antikoerper, CHGA antikoerper, CGA antikoerper, Chga antikoerper, chga antikoerper, chga.S antikoerper

Hintergrund

Description: The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides, vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown.

Aliases: CGA

Molekulargewicht

50.7kDa

Gen-ID

1113

HGNC

1113

UniProt

P10645

Pathways

Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling