CBX8 Antikörper (AA 17-222)
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- Target Alle CBX8 Antikörper anzeigen
- CBX8 (Chromobox Homolog 8 (CBX8))
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Bindungsspezifität
- AA 17-222
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CBX8 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human CBX8 (AA: 17-222 ) expressed in E. coli.
- Klon
- 9C3D4
- Isotyp
- IgG2b
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus." in: The EMBO journal, Vol. 26, Issue 6, pp. 1637-48, (2007) (PubMed).
: "
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Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus." in: The EMBO journal, Vol. 26, Issue 6, pp. 1637-48, (2007) (PubMed).
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- Target
- CBX8 (Chromobox Homolog 8 (CBX8))
- Andere Bezeichnung
- CBX8 (CBX8 Produkte)
- Synonyme
- cbx8 antikoerper, MGC147589 antikoerper, Pc3 antikoerper, PC3 antikoerper, RC1 antikoerper, chromobox 8 antikoerper, chromobox 8 S homeolog antikoerper, chromobox homolog 8a (Pc class homolog, Drosophila) antikoerper, cbx8 antikoerper, CBX8 antikoerper, Cbx8 antikoerper, cbx8.S antikoerper, cbx8a antikoerper
- Hintergrund
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Description: Chromobox homolog 8 (CBX8), a Polycomb Group protein that interacts with MLL-AF9 and TIP60, plays an essential role in MLL-AF9 transcriptional regulation and leukemogenesis. CBX8, which is part of one of the PRC1 complexes, regulates proliferation of diploid human and mouse fibroblasts through direct binding to the INK4A-ARF locus. , ,
Aliases: PC3, RC1
- Molekulargewicht
- 43.4 kDa
- Gen-ID
- 57332
- HGNC
- 57332
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