PDE1B Antikörper (AA 370-536)

Produktnummer ABIN1724781

Produktdetails anti-PDE1B Antikörper

Target: PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))

Bindungsspezifität: AA 370-536

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PDE1B Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Verwendungszweck: PDE1B Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human PDE1B (AA: 370-536 ) expressed in E. Coli.

Klon: 5C4A3

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-PDE1B Antikörper (ABIN1724781)

Vandeput, Wolda, Krall, Hambleton, Uher, McCaw, Radwanski, Florio, Movsesian: "Cyclic nucleotide phosphodiesterase PDE1C1 in human cardiac myocytes." in: The Journal of biological chemistry, Vol. 282, Issue 45, pp. 32749-57, (2007) (PubMed).

Details zu PDE1B

Target: PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))

Andere Bezeichnung: PDE1B (PDE1B Produkte)

Synonyme: 63kDa antikoerper, Pde1b1 antikoerper, PDE1B1 antikoerper, PDES1B antikoerper, Aop2 antikoerper, phosphodiesterase 1B, Ca2+-calmodulin dependent antikoerper, phosphodiesterase 1B antikoerper, Pde1b antikoerper, PDE1B antikoerper

Hintergrund:

Description: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Aliases: PDE1B1, PDES1B

Molekulargewicht: 61.4kDa

Gen-ID: 5153

HGNC: 5153

UniProt: Q01064

Pathways: Neurotrophin Signalübertragung, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma