Cytokeratin 5 Antikörper (AA 316-590)

Produktnummer ABIN1724790

Produktdetails anti-Cytokeratin 5 Antikörper

Target: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Bindungsspezifität: AA 316-590

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cytokeratin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human CK5 (AA: 316-590) expressed in E. coli.

Klon: 10C11E6

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-Cytokeratin 5 Antikörper (ABIN1724790)

Grin, OMalley, Mulligan: "Cytokeratin 5 and estrogen receptor immunohistochemistry as a useful adjunct in identifying atypical papillary lesions on breast needle core biopsy." in: The American journal of surgical pathology, Vol. 33, Issue 11, pp. 1615-23, (2009) (PubMed).

Sugiyama-Fukamatsu, Suzuki, Nakanishi, Iwatsuki: "Epidermolysis bullosa nevus arising in a patient with Dowling-Meara type epidermolysis bullosa simplex with a novel K5 mutation." in: The Journal of dermatology, Vol. 36, Issue 8, pp. 447-52, (2009) (PubMed).

Details zu Cytokeratin 5

Target: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Andere Bezeichnung: CK5 (KRT5 Produkte)

Synonyme: 3300001P10Rik antikoerper, AW146334 antikoerper, CK5 antikoerper, K5 antikoerper, Krt2-5 antikoerper, Tfip8 antikoerper, DDD antikoerper, DDD1 antikoerper, EBS2 antikoerper, KRT5A antikoerper, Sak57 antikoerper, ckii antikoerper, wu:fb02h09 antikoerper, wu:fj02d02 antikoerper, wu:fk78b12 antikoerper, zfCKII antikoerper, KRT75 antikoerper, CK-5 antikoerper, Keratin-5 antikoerper, keratin 5 antikoerper, Krt5 antikoerper, KRT5 antikoerper, krt5 antikoerper

Hintergrund:

Description: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. , ,

Aliases: K5, KRT5, DDD, EBS2, KRT5A

Molekulargewicht: 62.4 kDa

Gen-ID: 3852

HGNC: 3852