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Dynactin 4 Antikörper (AA 57-298)

DCTN4 Reaktivität: Human ELISA, WB, IHC, FACS, ICC Wirt: Maus Monoclonal 3G9D7 unconjugated
Produktnummer ABIN1724791
  • Target Alle Dynactin 4 (DCTN4) Antikörper anzeigen
    Dynactin 4 (DCTN4)
    Bindungsspezifität
    • 14
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 57-298
    Reaktivität
    • 37
    • 8
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    Human
    Wirt
    • 35
    • 2
    Maus
    Klonalität
    • 35
    • 2
    Monoklonal
    Konjugat
    • 17
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Dynactin 4 Antikörper ist unkonjugiert
    Applikation
    • 26
    • 22
    • 16
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Verwendungszweck
    DCTN4 Antibody
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human DCTN4 (AA: 57-298) expressed in E. Coli.
    Klon
    3G9D7
    Isotyp
    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Ayalon, Davis, Scotland, Bennett: "An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan." in: Cell, Vol. 135, Issue 7, pp. 1189-200, (2008) (PubMed).

    Lim, Cater, Mercer, La Fontaine: "Copper-dependent interaction of dynactin subunit p62 with the N terminus of ATP7B but not ATP7A." in: The Journal of biological chemistry, Vol. 281, Issue 20, pp. 14006-14, (2006) (PubMed).

  • Target
    Dynactin 4 (DCTN4)
    Andere Bezeichnung
    DCTN4 (DCTN4 Produkte)
    Synonyme
    DYN4 antikoerper, P62 antikoerper, MGC84654 antikoerper, zgc:112431 antikoerper, MGC97564 antikoerper, 1110001K06Rik antikoerper, 4930547K17Rik antikoerper, C130039E17Rik antikoerper, p62 antikoerper, dynactin subunit 4 antikoerper, dynactin subunit 4 L homeolog antikoerper, dynactin 4 antikoerper, dynactin 4, putative antikoerper, DCTN4 antikoerper, Dctn4 antikoerper, dctn4.L antikoerper, dctn4 antikoerper, PKH_031720 antikoerper
    Hintergrund

    Description: Dynactin 4 could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.The dynactin complex binds cargo, such as vesicles and organelles, to cytoplasmic dynein for retrograde microtubule-mediated trafficking and could feasibly be involved in the copper-regulated trafficking of ATP7B.

    Aliases: P62, DYN4

    Molekulargewicht
    52.3kDa
    Gen-ID
    51164
    HGNC
    51164
    UniProt
    Q9UJW0
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