Dynactin 4 Antikörper (AA 57-298)

Produktnummer ABIN1724791

Produktdetails anti-Dynactin 4 Antikörper

Target: Dynactin 4 (DCTN4)

Bindungsspezifität: AA 57-298

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Dynactin 4 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human DCTN4 (AA: 57-298) expressed in E. coli.

Klon: 3G9D7

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-Dynactin 4 Antikörper (ABIN1724791)

Ayalon, Davis, Scotland, Bennett: "An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan." in: Cell, Vol. 135, Issue 7, pp. 1189-200, (2008) (PubMed).

Lim, Cater, Mercer, La Fontaine: "Copper-dependent interaction of dynactin subunit p62 with the N terminus of ATP7B but not ATP7A." in: The Journal of biological chemistry, Vol. 281, Issue 20, pp. 14006-14, (2006) (PubMed).

Details zu Dynactin 4

Target: Dynactin 4 (DCTN4)

Andere Bezeichnung: DCTN4 (DCTN4 Produkte)

Synonyme: DYN4 antikoerper, P62 antikoerper, MGC84654 antikoerper, zgc:112431 antikoerper, MGC97564 antikoerper, 1110001K06Rik antikoerper, 4930547K17Rik antikoerper, C130039E17Rik antikoerper, p62 antikoerper, dynactin subunit 4 antikoerper, dynactin subunit 4 L homeolog antikoerper, dynactin 4 antikoerper, dynactin 4, putative antikoerper, DCTN4 antikoerper, Dctn4 antikoerper, dctn4.L antikoerper, dctn4 antikoerper, PKH_031720 antikoerper

Hintergrund:

Description: Dynactin 4 could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.The dynactin complex binds cargo, such as vesicles and organelles, to cytoplasmic dynein for retrograde microtubule-mediated trafficking and could feasibly be involved in the copper-regulated trafficking of ATP7B. , ,

Aliases: P62, DYN4

Molekulargewicht: 52.3 kDa

Gen-ID: 51164

HGNC: 51164