Integrin beta 4 Antikörper (AA 1619-1822)
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- Target Alle Integrin beta 4 (ITGB4) Antikörper anzeigen
- Integrin beta 4 (ITGB4)
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Bindungsspezifität
- AA 1619-1822
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Integrin beta 4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human ITGB4 (AA: 1619-1822) expressed in E. coli.
- Klon
- 10B10D5
- Isotyp
- IgG1
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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Downregulation of integrin β4 decreases the ability of airway epithelial cells to present antigens." in: PLoS ONE, Vol. 7, Issue 4, pp. e32060, (2012) (PubMed).
: "
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Downregulation of integrin β4 decreases the ability of airway epithelial cells to present antigens." in: PLoS ONE, Vol. 7, Issue 4, pp. e32060, (2012) (PubMed).
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- Target
- Integrin beta 4 (ITGB4)
- Andere Bezeichnung
- ITGB4 (ITGB4 Produkte)
- Synonyme
- AA407042 antikoerper, C230078O20 antikoerper, CD104 antikoerper, integrin subunit beta 4 antikoerper, integrin beta 4 antikoerper, ITGB4 antikoerper, Itgb4 antikoerper
- Hintergrund
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Description: Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. , , ,
Aliases: CD104
- Molekulargewicht
- 202 kDa
- Gen-ID
- 3691
- HGNC
- 3691
- Pathways
- Integrin Complex
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