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Integrin beta 4 Antikörper (AA 1619-1822)

ITGB4 Reaktivität: Human WB, IHC, FACS, ELISA Wirt: Maus Monoclonal 10B10D5 unconjugated
Produktnummer ABIN1724805
  • Target Alle Integrin beta 4 (ITGB4) Antikörper anzeigen
    Integrin beta 4 (ITGB4)
    Bindungsspezifität
    • 15
    • 10
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1619-1822
    Reaktivität
    • 84
    • 30
    • 25
    • 3
    • 3
    Human
    Wirt
    • 56
    • 37
    • 15
    • 2
    Maus
    Klonalität
    • 59
    • 51
    Monoklonal
    Konjugat
    • 58
    • 10
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Integrin beta 4 Antikörper ist unkonjugiert
    Applikation
    • 54
    • 48
    • 32
    • 31
    • 21
    • 18
    • 15
    • 13
    • 13
    • 9
    • 8
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human ITGB4 (AA: 1619-1822) expressed in E. coli.
    Klon
    10B10D5
    Isotyp
    IgG1
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Liu, Qin, Liu, Xiang: "Downregulation of integrin β4 decreases the ability of airway epithelial cells to present antigens." in: PLoS ONE, Vol. 7, Issue 4, pp. e32060, (2012) (PubMed).

  • Target
    Integrin beta 4 (ITGB4)
    Andere Bezeichnung
    ITGB4 (ITGB4 Produkte)
    Synonyme
    AA407042 antikoerper, C230078O20 antikoerper, CD104 antikoerper, integrin subunit beta 4 antikoerper, integrin beta 4 antikoerper, ITGB4 antikoerper, Itgb4 antikoerper
    Hintergrund

    Description: Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. , , ,

    Aliases: CD104

    Molekulargewicht
    202 kDa
    Gen-ID
    3691
    HGNC
    3691
    Pathways
    Integrin Complex
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