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TP53BP1 Antikörper (AA 574-773)

TP53BP1 Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Maus Monoclonal 6B3E10 unconjugated
Produktnummer ABIN1724820
  • Target Alle TP53BP1 Antikörper anzeigen
    TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))
    Bindungsspezifität
    • 32
    • 21
    • 15
    • 11
    • 8
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 574-773
    Reaktivität
    • 104
    • 63
    • 61
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 108
    • 8
    • 2
    • 1
    Maus
    Klonalität
    • 102
    • 17
    Monoklonal
    Konjugat
    • 58
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser TP53BP1 Antikörper ist unkonjugiert
    Applikation
    • 44
    • 29
    • 27
    • 27
    • 25
    • 18
    • 17
    • 12
    • 10
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
    Verwendungszweck
    TP53BP1 Antibody
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human TP53BP1 (AA: 574-773) expressed in E. Coli.
    Klon
    6B3E10
    Isotyp
    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Nakada, Yonamine, Matsuo: "RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1." in: Cancer research, Vol. 72, Issue 19, pp. 4974-83, (2012) (PubMed).

    Mok, Henderson: "The in vivo dynamic interplay of MDC1 and 53BP1 at DNA damage-induced nuclear foci." in: The international journal of biochemistry & cell biology, Vol. 44, Issue 9, pp. 1398-409, (2012) (PubMed).

  • Target
    TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))
    Andere Bezeichnung
    TP53BP1 (TP53BP1 Produkte)
    Synonyme
    TP53BP1 antikoerper, MGC160112 antikoerper, 53BP1 antikoerper, Tp53bp1 antikoerper, m53BP1 antikoerper, p202 antikoerper, Trp53bp1 antikoerper, tumor protein p53 binding protein 1 antikoerper, tumor suppressor p53-binding protein 1 antikoerper, tumor protein p53 binding protein 1 (predicted), 5 prime antikoerper, transformation related protein 53 binding protein 1 antikoerper, TP53BP1 antikoerper, tp53bp1 antikoerper, LOC100550605 antikoerper, Trp53bp1 antikoerper, Tp53bp1 antikoerper
    Hintergrund

    Description: T protein p53 binding protein 1 may have a role in checkpoint signaling during mitosis,enhance TP53-mediated transcriptional activation and play a role in the response to DNA damage.

    Aliases: p202, 53BP1

    Molekulargewicht
    213.6kDa
    Gen-ID
    7158
    HGNC
    7158
    UniProt
    Q12888
    Pathways
    DNA Reparatur
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