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NG2 Antikörper (AA 2247-2308)

MCSP Reaktivität: Human WB, ELISA, FACS Wirt: Maus Monoclonal 7G4E5 unconjugated
Produktnummer ABIN1724837
  • Target Alle NG2 (MCSP) Antikörper anzeigen
    NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
    Bindungsspezifität
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2247-2308
    Reaktivität
    • 45
    • 23
    • 17
    • 1
    Human
    Wirt
    • 42
    • 14
    Maus
    Klonalität
    • 32
    • 23
    • 1
    Monoklonal
    Konjugat
    • 27
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser NG2 Antikörper ist unkonjugiert
    Applikation
    • 30
    • 20
    • 10
    • 10
    • 8
    • 7
    • 7
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human CSPG4 (AA: 2247-2308) expressed in E. coli.
    Klon
    7G4E5
    Isotyp
    IgG1
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Wang, Katayama, Wang, Yu, Favoino, Sakakura, Favole, Tsuchikawa, Silver, Watkins, Kageshita, Ferrone: "Functional characterization of an scFv-Fc antibody that immunotherapeutically targets the common cancer cell surface proteoglycan CSPG4." in: Cancer research, Vol. 71, Issue 24, pp. 7410-22, (2011) (PubMed).

    Price, Colvin Wanshura, Yang, Carlson, Xiang, Li, Ferrone, Dudek, Turley, McCarthy: "CSPG4, a potential therapeutic target, facilitates malignant progression of melanoma." in: Pigment cell & melanoma research, Vol. 24, Issue 6, pp. 1148-57, (2011) (PubMed).

  • Target
    NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
    Andere Bezeichnung
    CSPG4 (MCSP Produkte)
    Synonyme
    HMW-MAA antikoerper, MCSP antikoerper, MCSPG antikoerper, MEL-CSPG antikoerper, MSK16 antikoerper, NG2 antikoerper, 4732461B14Rik antikoerper, AN2 antikoerper, Ng2 antikoerper, HSMCSGEN1 antikoerper, MCS antikoerper, chondroitin sulfate proteoglycan 4 antikoerper, sperm mitochondria associated cysteine rich protein antikoerper, CSPG4 antikoerper, Cspg4 antikoerper, SMCP antikoerper
    Hintergrund

    Description: A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.

    Aliases: NG2, MCSP, MCSPG, MSK16, HMW-MAA, MEL-CSPG

    Molekulargewicht
    250.0 kDa
    Gen-ID
    1464
    HGNC
    1464
    Pathways
    Glycosaminoglycan Metabolic Process
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