NG2 Antikörper (AA 2247-2308)

Produktnummer ABIN1724837

Produktdetails anti-NG2 Antikörper

Target: NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))

Bindungsspezifität: AA 2247-2308

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NG2 Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS)

Verwendungszweck: CSPG4 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human CSPG4 (AA: 2247-2308) expressed in E. Coli.

Klon: 7G4E5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-NG2 Antikörper (ABIN1724837)

Wang, Katayama, Wang, Yu, Favoino, Sakakura, Favole, Tsuchikawa, Silver, Watkins, Kageshita, Ferrone: "Functional characterization of an scFv-Fc antibody that immunotherapeutically targets the common cancer cell surface proteoglycan CSPG4." in: Cancer research, Vol. 71, Issue 24, pp. 7410-22, (2011) (PubMed).

Price, Colvin Wanshura, Yang, Carlson, Xiang, Li, Ferrone, Dudek, Turley, McCarthy: "CSPG4, a potential therapeutic target, facilitates malignant progression of melanoma." in: Pigment cell & melanoma research, Vol. 24, Issue 6, pp. 1148-57, (2011) (PubMed).

Details zu NG2

Target: NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))

Andere Bezeichnung: CSPG4 (MCSP Produkte)

Synonyme: HMW-MAA antikoerper, MCSP antikoerper, MCSPG antikoerper, MEL-CSPG antikoerper, MSK16 antikoerper, NG2 antikoerper, 4732461B14Rik antikoerper, AN2 antikoerper, Ng2 antikoerper, HSMCSGEN1 antikoerper, MCS antikoerper, chondroitin sulfate proteoglycan 4 antikoerper, sperm mitochondria associated cysteine rich protein antikoerper, CSPG4 antikoerper, Cspg4 antikoerper, SMCP antikoerper

Hintergrund:

Description: A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.

Aliases: NG2, MCSP, MCSPG, MSK16, HMW-MAA, MEL-CSPG

Molekulargewicht: 250.0kDa

Gen-ID: 1464

HGNC: 1464

UniProt: Q6UVK1

Pathways: Glycosaminoglycan Metabolic Process