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MCAM Antikörper (AA 84-189)

Name: MCAM Antikörper (AA 84-189)
Brand: antibodies-online
SKU: ABIN1724844
Price: 614.71 EUR
Availability: InStock

MCAM Reaktivität: Human FACS, IHC, WB, ELISA Wirt: Maus Monoclonal 6C3E6 unconjugated

Immunohistochemical analysis of paraffin-embedded liver cancer tissues using MCAM mouse mAb with DAB staining. (MCAM Antikörper (AA 84-189))

IHC

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (MCAM Antikörper (AA 84-189))

ELISA

Flow cytometric analysis of MCF-7 cells using MCAM mouse mAb (green) and negative control (red). (MCAM Antikörper (AA 84-189))

FACS

Western blot analysis using MCAM mouse mAb against HUVE-12 (1), EVC-304 (2), HELA (3) and MCF-7 (4) cell lysate. (MCAM Antikörper (AA 84-189))

Western blot analysis using MCAM mAb against human MCAM recombinant protein. (MCAM Antikörper (AA 84-189))

Western blot analysis using MCAM mAb against HEK293 (1) and MCAM (AA: 84-189)-hIgGFc transfected HEK293 (2) cell lysate. (MCAM Antikörper (AA 84-189))

Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using MCAM mouse mAb with DAB staining. (MCAM Antikörper (AA 84-189))

IHC

7 Abbildungen

(2 Referenzen)

Produktnummer ABIN1724844

Datenblatt (PDF)

Target Alle MCAM Antikörper anzeigen

MCAM (Melanoma Cell Adhesion Molecule (MCAM))
Bindungsspezifität
16

13

11

6

4

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 84-189
Reaktivität
133

53

47

14

14

9

8

7

6

2
Human
Wirt
95

62

8

1

1
Maus
Passende Sekundärantikörper
Klonalität
88

79
Monoklonal
Konjugat
70

14

14

11

6

5

4

4

4

3

3

3

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser MCAM Antikörper ist unkonjugiert
Applikation
85

79

68

42

22

20

14

10

10

5

4

4

3

3

2

1

1

1

1

1
Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Verwendungszweck

MCAM Antibody

Aufreinigung

Purified antibody

Immunogen

Purified recombinant fragment of human MCAM (AA: 84-189) expressed in E. Coli.

Klon

6C3E6

Isotyp

IgG1
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 50-646) antibody
MCAM Reaktivität: Human FACS, WB, IF, ELISA Wirt: Maus Monoclonal 4D10C7 unconjugated

anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 447-646) antibody
MCAM Reaktivität: Human IHC, WB, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Melanoma Cell Adhesion Molecule (MCAM) antibody
MCAM Reaktivität: Human FACS, IHC, WB, IF, ELISA Wirt: Kaninchen Monoclonal 8A10 unconjugated Recombinant Antibody

anti-Melanoma Cell Adhesion Molecule (MCAM) antibody
MCAM Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 1-646) antibody
MCAM Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated

anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 226-374) antibody
MCAM Reaktivität: Human IHC, StM Wirt: Maus Monoclonal MCAM-3046 unconjugated

anti-Melanoma Cell Adhesion Molecule (MCAM) antibody
MCAM Reaktivität: Human, Maus, Ratte IHC, WB Wirt: Kaninchen Polyclonal unconjugated

anti-Melanoma Cell Adhesion Molecule (MCAM) antibody
MCAM Reaktivität: Human, Maus, Kaninchen, Hund FACS, WB, IHC (p), IP, IHC (fro), ICC Wirt: Maus Monoclonal P1H12 unconjugated

anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 201-300) antibody
MCAM Reaktivität: Human, Ratte FACS, WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 161-189) antibody
MCAM Reaktivität: Human FACS, WB, IHC (p) Wirt: Kaninchen Polyclonal RB20606 unconjugated

Applikationshinweise

ELISA: 1/10000
FCM: 1/200 - 1/400

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Wang, Yan: "CD146, a multi-functional molecule beyond adhesion." in: Cancer letters, Vol. 330, Issue 2, pp. 150-62, (2013) (PubMed).

Jouve, Despoix, Espeli, Gauthier, Cypowyj, Fallague, Schiff, Dignat-George, Vély, Leroyer: "The involvement of CD146 and its novel ligand Galectin-1 in apoptotic regulation of endothelial cells." in: The Journal of biological chemistry, Vol. 288, Issue 4, pp. 2571-9, (2013) (PubMed).
Target

MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Andere Bezeichnung

MCAM (MCAM Produkte)

Synonyme

CD146 antikoerper, MUC18 antikoerper, Muc18 antikoerper, 1-gicerin antikoerper, AV025631 antikoerper, CD149 antikoerper, s-endo antikoerper, s-gicerin antikoerper, cd146 antikoerper, gicerin antikoerper, id:ibd3512 antikoerper, mcam antikoerper, MCAM antikoerper, melanoma cell adhesion molecule antikoerper, melanoma cell adhesion molecule b antikoerper, MCAM antikoerper, Mcam antikoerper, mcamb antikoerper

Hintergrund

Description: The protein encoded by this gene plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

Aliases: CD146, MUC18

Molekulargewicht

71.6kDa

Gen-ID

4162

HGNC

4162

UniProt

P43121