IL3RA Antikörper (AA 200-305)

Produktnummer ABIN1724855

Produktdetails anti-IL3RA Antikörper

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Bindungsspezifität: AA 200-305

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL3RA Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Verwendungszweck: IL3RA Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human IL3RA (AA: 200-305) expressed in E. Coli.

Klon: 8E11C5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-IL3RA Antikörper (ABIN1724855)

Venkataraman, Aguhar, Kreitman, Yuan, Stetler-Stevenson: "Characteristic CD103 and CD123 expression pattern defines hairy cell leukemia: usefulness of CD123 and CD103 in the diagnosis of mature B-cell lymphoproliferative disorders." in: American journal of clinical pathology, Vol. 136, Issue 4, pp. 625-30, (2011) (PubMed).

Yue, Fu, Wang, Li, Hu, Fu, Shao: "Expression of CD123 and CD114 on the bone marrow cells of patients with myelodysplastic syndrome." in: Chinese medical journal, Vol. 123, Issue 15, pp. 2034-7, (2010) (PubMed).

Details zu IL3RA

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Andere Bezeichnung: IL3RA (IL3RA Produkte)

Synonyme: CD123 antikoerper, IL3R antikoerper, IL3RAY antikoerper, IL3RX antikoerper, IL3RY antikoerper, hIL-3Ra antikoerper, CDw123 antikoerper, SUT-1 antikoerper, Cyrl antikoerper, interleukin 3 receptor subunit alpha antikoerper, interleukin 3 receptor, alpha chain antikoerper, IL3RA antikoerper, Il3ra antikoerper

Hintergrund:

Description: The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found.

Aliases: IL3R, CD123, IL3RX, IL3RY, IL3RAY, hIL-3Ra

Molekulargewicht: 43.3kDa

Gen-ID: 3563

HGNC: 3563

UniProt: P26951

Pathways: JAK-STAT Signalweg