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Osteoactivin Antikörper (AA 31-260)

GPNMB Reaktivität: Human WB, ELISA, IHC Wirt: Maus Monoclonal 7C10E5 unconjugated
Produktnummer ABIN1724859
  • Target Alle Osteoactivin (GPNMB) Antikörper anzeigen
    Osteoactivin (GPNMB)
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-260
    Reaktivität
    • 58
    • 25
    • 24
    • 7
    • 7
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    Human
    Wirt
    • 46
    • 13
    Maus
    Klonalität
    • 47
    • 12
    Monoklonal
    Konjugat
    • 20
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Osteoactivin Antikörper ist unkonjugiert
    Applikation
    • 46
    • 21
    • 13
    • 13
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human GPNMB (AA: 31-260) expressed in E. coli.
    Klon
    7C10E5
    Isotyp
    IgG1
    Top Product
    Discover our top product GPNMB Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Tsui, Chang, Feng, Chang, Juang: "Glycoprotein transmembrane nmb: an androgen-downregulated gene attenuates cell invasion and tumorigenesis in prostate carcinoma cells." in: The Prostate, Vol. 72, Issue 13, pp. 1431-42, (2012) (PubMed).

    Williams, Esmaeli, Soheili, Simantov, Gombos, Bedikian, Hwu: "GPNMB expression in uveal melanoma: a potential for targeted therapy." in: Melanoma research, Vol. 20, Issue 3, pp. 184-90, (2010) (PubMed).

  • Target
    Osteoactivin (GPNMB)
    Andere Bezeichnung
    GPNMB (GPNMB Produkte)
    Synonyme
    HGFIN antikoerper, NMB antikoerper, DC-HIL antikoerper, Dchil antikoerper, ipd antikoerper, glycoprotein nmb antikoerper, glycoprotein (transmembrane) nmb antikoerper, glycoprotein nmb L homeolog antikoerper, Gpnmb antikoerper, GPNMB antikoerper, gpnmb.L antikoerper
    Hintergrund

    Description: The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. ,

    Aliases: NMB, HGFIN

    Molekulargewicht
    64 kDa
    Gen-ID
    10457
    HGNC
    10457
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