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Osteoactivin Antikörper (AA 31-260)

Name: Osteoactivin Antikörper (AA 31-260)
Brand: antibodies-online
SKU: ABIN1724859
Price: 614.71 EUR
Availability: InStock

GPNMB Reaktivität: Human WB, ELISA, IHC Wirt: Maus Monoclonal 7C10E5 unconjugated

Western blot analysis using GPNMB mouse mAb against PANC1 (1) and PC-3 (2) cell lysate. (Osteoactivin Antikörper (AA 31-260))

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (Osteoactivin Antikörper (AA 31-260))

ELISA

Western blot analysis using GPNMB mAb against human GPNMB recombinant protein. (Osteoactivin Antikörper (AA 31-260))

Western blot analysis using GPNMB mAb against HEK293 (1) and GPNMB (AA: 31-260)-hIgGFc transfected HEK293 (2) cell lysate. (Osteoactivin Antikörper (AA 31-260))

Immunohistochemical analysis of paraffin-embedded breast cancer tissues using GPNMB mouse mAb with DAB staining. (Osteoactivin Antikörper (AA 31-260))

IHC

Immunohistochemical analysis of paraffin-embedded esophagus cancer tissues using GPNMB mouse mAb with DAB staining. (Osteoactivin Antikörper (AA 31-260))

IHC

6 Abbildungen

(2 Referenzen)

Produktnummer ABIN1724859

Datenblatt (PDF)

Target Alle Osteoactivin (GPNMB) Antikörper anzeigen

Osteoactivin (GPNMB)
Bindungsspezifität
15

8

7

6

5

3

2

2

1

1

1

1

1

1
AA 31-260
Reaktivität
58

25

24

7

7

5

4

4

4

2

2

1
Human
Wirt
46

13
Maus
Passende Sekundärantikörper
Klonalität
47

12
Monoklonal
Konjugat
20

4

4

4

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser Osteoactivin Antikörper ist unkonjugiert
Applikation
46

21

13

13

7

6

4

4

4

3

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Verwendungszweck

GPNMB Antibody

Aufreinigung

Purified antibody

Immunogen

Purified recombinant fragment of human GPNMB (AA: 31-260) expressed in E. Coli.

Klon

7C10E5

Isotyp

IgG1

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anti-Osteoactivin (GPNMB) (AA 104-203) antibody
GPNMB Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1A8 unconjugated

anti-Osteoactivin (GPNMB) (N-Term) antibody
GPNMB Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Hund, Kaninchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Osteoactivin (GPNMB) (AA 541-569), (C-Term) antibody
GPNMB Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB36977 unconjugated

anti-Osteoactivin (GPNMB) (AA 104-203) antibody
GPNMB Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated

anti-Osteoactivin (GPNMB) (AA 1-572) antibody
GPNMB Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 3A5 unconjugated

anti-Osteoactivin (GPNMB) (AA 50-99) antibody
GPNMB Reaktivität: Human, Maus, Rind (Kuh), Pferd, Kaninchen, Hamster WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Osteoactivin (GPNMB) (AA 1-572) antibody
GPNMB Reaktivität: Human WB, ELISA, IHC, IHC (p) Wirt: Maus Monoclonal 3A5 unconjugated

anti-Osteoactivin (GPNMB) (AA 22-260) antibody
GPNMB Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated

anti-Osteoactivin (GPNMB) (AA 74-123) antibody
GPNMB Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Hund, Kaninchen, Zebrafisch (Danio rerio), Hamster, Fledermaus WB Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

ELISA: 1/10000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Tsui, Chang, Feng, Chang, Juang: "Glycoprotein transmembrane nmb: an androgen-downregulated gene attenuates cell invasion and tumorigenesis in prostate carcinoma cells." in: The Prostate, Vol. 72, Issue 13, pp. 1431-42, (2012) (PubMed).

Williams, Esmaeli, Soheili, Simantov, Gombos, Bedikian, Hwu: "GPNMB expression in uveal melanoma: a potential for targeted therapy." in: Melanoma research, Vol. 20, Issue 3, pp. 184-90, (2010) (PubMed).
Target

Osteoactivin (GPNMB)

Andere Bezeichnung

GPNMB (GPNMB Produkte)

Synonyme

HGFIN antikoerper, NMB antikoerper, DC-HIL antikoerper, Dchil antikoerper, ipd antikoerper, glycoprotein nmb antikoerper, glycoprotein (transmembrane) nmb antikoerper, glycoprotein nmb L homeolog antikoerper, Gpnmb antikoerper, GPNMB antikoerper, gpnmb.L antikoerper

Hintergrund

Description: The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
Aliases: NMB, HGFIN

Molekulargewicht

64kDa

Gen-ID

10457

HGNC

10457

UniProt

Q14956