PLAGL1 Antikörper (AA 118-222)

Produktnummer ABIN1724869

Produktdetails anti-PLAGL1 Antikörper

Target: PLAGL1 (Pleiomorphic Adenoma Gene-Like 1 (PLAGL1))

Bindungsspezifität: AA 118-222

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PLAGL1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Verwendungszweck: PLAGL1 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human PLAGL1 (AA: 118-222) expressed in E. Coli.

Klon: 8D8C5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-PLAGL1 Antikörper (ABIN1724869)

Liu, Hsieh, Liu, Chang, Lin, Wang, Huang: "Zac1, an Sp1-like protein, regulates human p21(WAF1/Cip1) gene expression in HeLa cells." in: Experimental cell research, Vol. 317, Issue 20, pp. 2925-37, (2011) (PubMed).

Details zu PLAGL1

Target: PLAGL1 (Pleiomorphic Adenoma Gene-Like 1 (PLAGL1))

Andere Bezeichnung: PLAGL1 (PLAGL1 Produkte)

Synonyme: PLAGL1 antikoerper, LOT1 antikoerper, ZAC antikoerper, ZAC1 antikoerper, Lot1 antikoerper, Zac1 antikoerper, PLAG1 like zinc finger 1 antikoerper, uncharacterized LOC100350914 antikoerper, pleiomorphic adenoma gene-like 1 antikoerper, PLAGL1 antikoerper, LOC100350914 antikoerper, Plagl1 antikoerper

Hintergrund:

Description: This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activities. It has been shown to have anti-proliferative properties, and thus thought to function as a tumor suppressor. In addition, overexpression of this gene during fetal development is believed to underlie the rare disorder, transient neonatal diabetes mellitus (TNDM). This gene is imprinted, with preferential expression of the paternal allele in many tissues, however, biallelic expression has been noted in peripheral blood leucocytes. A recent study reports that tissue-specific imprinting results from variable utilization of monoallelic and biallelic promoters. Many transcript variants differing in the 5' UTR and encoding two different isoforms, have been found for this gene.

Aliases: ZAC, LOT1, ZAC1

Molekulargewicht: 50.8kDa

Gen-ID: 5325

HGNC: 5325

UniProt: Q9UM63