CD74 Antikörper (AA 1-106)
(2 Referenzen)-
- Target Alle CD74 Antikörper anzeigen
- CD74 (HLA-DR-gamma (CD74))
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Bindungsspezifität
- AA 1-106
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD74 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Western Blotting (WB), ELISA
- Verwendungszweck
- CD74 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human CD74 (AA: 1-106) expressed in E. Coli.
- Klon
- 2D1B11
- Isotyp
- IgG1
- Top Product
- Discover our top product CD74 Primärantikörper
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anti-HLA-DR-gamma (CD74) (AA 1-106) antibody
CD74 Reaktivität: Human FACS, WB, ELISA, ICC Wirt: Maus Monoclonal 2D1B3 unconjugated
anti-HLA-DR-gamma (CD74) (AA 78-222) antibodyCD74 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-HLA-DR-gamma (CD74) (AA 64-205) antibodyCD74 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-HLA-DR-gamma (CD74) antibodyCD74 Reaktivität: Maus, Ratte IF, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-HLA-DR-gamma (CD74) antibodyCD74 Reaktivität: Human FACS, WB, IF, IHC, IP, ICC Wirt: Maus Monoclonal PIN-1 unconjugated
anti-HLA-DR-gamma (CD74) (N-Term) antibodyCD74 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-HLA-DR-gamma (CD74) antibodyCD74 Reaktivität: Human, Maus, Pavian FACS, IF, IHC, StM Wirt: Maus Monoclonal LN-2 unconjugated
anti-HLA-DR-gamma (CD74) (AA 73-232) antibodyCD74 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-HLA-DR-gamma (CD74) (AA 65-277) antibodyCD74 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-HLA-DR-gamma (CD74) antibody (HRP)CD74 Reaktivität: Human FACS, WB, IF, IHC, IP, ICC Wirt: Maus Monoclonal PIN-1 HRP
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "CD74: a potential novel target for triple-negative breast cancer." in: Tumour biology, Vol. 33, Issue 6, pp. 2273-7, (2012) (PubMed).
: "CD74 and macrophage migration inhibitory factor as therapeutic targets in gastric cancer." in: World journal of gastroenterology : WJG, Vol. 18, Issue 18, pp. 2253-61, (2012) (PubMed).
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: "CD74: a potential novel target for triple-negative breast cancer." in: Tumour biology, Vol. 33, Issue 6, pp. 2273-7, (2012) (PubMed).
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- Target
- CD74 (HLA-DR-gamma (CD74))
- Andere Bezeichnung
- CD74 (CD74 Produkte)
- Hintergrund
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Description: The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Aliases: II, DHLAG, HLADG, Ia-GAMMA
- Molekulargewicht
- 33.5kDa
- Gen-ID
- 972
- HGNC
- 972
- UniProt
- P04233
- Pathways
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
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