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CA9 Antikörper (AA 37-186)

Name: CA9 Antikörper (AA 37-186)
Brand: antibodies-online
SKU: ABIN1724882
Price: 614.71 EUR
Availability: InStock

CA9 Reaktivität: Human WB, ELISA, FACS Wirt: Maus Monoclonal 10F7A8 unconjugated

Western blot analysis using CA9 mouse mAb against A431 (1) and SW620 (2) cell lysate. (CA9 Antikörper (AA 37-186))

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (CA9 Antikörper (AA 37-186))

ELISA

Flow cytometric analysis of NTERA-2 cells using CA9 mouse mAb (green) and negative control (red). (CA9 Antikörper (AA 37-186))

FACS

Western blot analysis using CA9 mAb against human CA9 recombinant protein. (CA9 Antikörper (AA 37-186))

Western blot analysis using CA9 mAb against HEK293 (1) and CA9 (AA: 37-186)-hIgGFc transfected HEK293 (2) cell lysate. (CA9 Antikörper (AA 37-186))

5 Abbildungen

(2 Referenzen)

Produktnummer ABIN1724882

Datenblatt (PDF)

Target Alle CA9 Antikörper anzeigen

CA9 (Carbonic Anhydrase IX (CA9))
Bindungsspezifität
15

7

5

5

5

4

3

2

2

2

1

1

1

1

1

1
AA 37-186
Reaktivität
86

25

21

14

5

4

4
Human
Wirt
70

34
Maus
Passende Sekundärantikörper
Klonalität
59

45
Monoklonal
Konjugat
49

9

4

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CA9 Antikörper ist unkonjugiert
Applikation
69

28

27

26

23

14

13

11

10

9

6

4

3

2

1

1

1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Verwendungszweck

CA9 Antibody

Aufreinigung

Purified antibody

Immunogen

Purified recombinant fragment of human CA9 (AA: 37-186) expressed in E. Coli.

Klon

10F7A8

Isotyp

IgG1

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anti-Carbonic Anhydrase IX (CA9) antibody
CA9 Reaktivität: Human WB, ELISA, IP Wirt: Maus Monoclonal unconjugated

Applikationshinweise

ELISA: 1/10000
FCM: 1/200 - 1/400

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Neumeister, Sullivan, Lindner, Lezon-Geyda, Li, Zavada, Martel, Glazer, Tuck, Rimm, Harris: "Hypoxia-induced protein CAIX is associated with somatic loss of BRCA1 protein and pathway activity in triple negative breast cancer." in: Breast cancer research and treatment, Vol. 136, Issue 1, pp. 67-75, (2012) (PubMed).

Pinheiro, Sousa, Albergaria, Paredes, Dufloth, Vieira, Schmitt, Baltazar: "GLUT1 and CAIX expression profiles in breast cancer correlate with adverse prognostic factors and MCT1 overexpression." in: Histology and histopathology, Vol. 26, Issue 10, pp. 1279-86, (2011) (PubMed).
Target

CA9 (Carbonic Anhydrase IX (CA9))

Andere Bezeichnung

CA9 (CA9 Produkte)

Synonyme

CA9 antikoerper, CAIX antikoerper, Ca9 antikoerper, MN/CA9 antikoerper, MN antikoerper, carbonic anhydrase 9 antikoerper, CA9 antikoerper, CAH9 antikoerper, Car9 antikoerper

Hintergrund

Description: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.
Aliases: MN, CAIX

Molekulargewicht

49.7kDa

Gen-ID

768

HGNC

768

UniProt

Q16790