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CA9 Antikörper (AA 37-186)

CA9 Reaktivität: Human WB, IHC, ELISA Wirt: Maus Monoclonal 7C4A5 unconjugated
Produktnummer ABIN1724883
  • Target Alle CA9 Antikörper anzeigen
    CA9 (Carbonic Anhydrase IX (CA9))
    Bindungsspezifität
    • 15
    • 7
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 37-186
    Reaktivität
    • 86
    • 25
    • 21
    • 14
    • 5
    • 4
    • 4
    Human
    Wirt
    • 70
    • 34
    Maus
    Klonalität
    • 59
    • 45
    Monoklonal
    Konjugat
    • 49
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CA9 Antikörper ist unkonjugiert
    Applikation
    • 69
    • 29
    • 26
    • 26
    • 23
    • 14
    • 13
    • 11
    • 10
    • 9
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Verwendungszweck
    CA9 Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human CA9 (AA: 37-186) expressed in E. Coli.
    Klon
    7C4A5
    Isotyp
    IgG1
  • Applikationshinweise
    ELISA: 1/10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Neumeister, Sullivan, Lindner, Lezon-Geyda, Li, Zavada, Martel, Glazer, Tuck, Rimm, Harris: "Hypoxia-induced protein CAIX is associated with somatic loss of BRCA1 protein and pathway activity in triple negative breast cancer." in: Breast cancer research and treatment, Vol. 136, Issue 1, pp. 67-75, (2012) (PubMed).

    Pinheiro, Sousa, Albergaria, Paredes, Dufloth, Vieira, Schmitt, Baltazar: "GLUT1 and CAIX expression profiles in breast cancer correlate with adverse prognostic factors and MCT1 overexpression." in: Histology and histopathology, Vol. 26, Issue 10, pp. 1279-86, (2011) (PubMed).

  • Target
    CA9 (Carbonic Anhydrase IX (CA9))
    Andere Bezeichnung
    CA9 (CA9 Produkte)
    Synonyme
    CA9 antikoerper, CAIX antikoerper, Ca9 antikoerper, MN/CA9 antikoerper, MN antikoerper, carbonic anhydrase 9 antikoerper, CA9 antikoerper, CAH9 antikoerper, Car9 antikoerper
    Hintergrund

    Description: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.

    Aliases: MN, CAIX

    Molekulargewicht
    49.7kDa
    Gen-ID
    768
    HGNC
    768
    UniProt
    Q16790
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