CD22 Antikörper (AA 621-725)
(2 Referenzen)-
- Target Alle CD22 Antikörper anzeigen
- CD22 (CD22 Molecule (CD22))
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Bindungsspezifität
- AA 621-725
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD22 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human CD22 (AA: 621-725) expressed in E. coli.
- Klon
- 1A3A11
- Isotyp
- IgG1
- Top Product
- Discover our top product CD22 Primärantikörper
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anti-CD22 Molecule (CD22) (AA 621-725) antibody
CD22 Reaktivität: Human FACS, WB, ELISA, IHC, ICC Wirt: Maus Monoclonal 2H1C4 unconjugated
anti-CD22 Molecule (CD22) (AA 52-178) antibodyCD22 Reaktivität: Human FACS, WB, ELISA, IHC, IF, Coat, StM Wirt: Maus Monoclonal BLCAM-1795 unconjugated
anti-CD22 Molecule (CD22) (AA 52-178) antibodyCD22 Reaktivität: Human FACS, WB, ELISA, IHC, IF, Coat Wirt: Maus Monoclonal BLCAM-1796 unconjugated
anti-CD22 Molecule (CD22) antibodyCD22 Reaktivität: Human, Non-Human Primate FACS, WB, IP Wirt: Maus Monoclonal MEM-01 unconjugated
anti-CD22 Molecule (CD22) antibody (PE)CD22 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal MEM-01 PE
anti-CD22 Molecule (CD22) antibody (FITC)CD22 Reaktivität: Human FACS Wirt: Maus Monoclonal IS7 FITC
anti-CD22 Molecule (CD22) (AA 708-847) antibodyCD22 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-CD22 Molecule (CD22) antibodyCD22 Reaktivität: Human, Maus, Ratte, Affe, Hund WB, IHC, IHC (p) Wirt: Maus Monoclonal 4C3 unconjugated
anti-CD22 Molecule (CD22) (AA 20-687) antibodyCD22 Reaktivität: Human FACS, WB, ELISA, IF, IP Wirt: Kaninchen Monoclonal DM13 unconjugated
anti-CD22 Molecule (CD22) (AA 52-178) antibodyCD22 Reaktivität: Human IHC Wirt: Kaninchen Monoclonal MSVA-022R unconjugated Recombinant Antibody
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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: "CD22 antigen is broadly expressed on lung cancer cells and is a target for antibody-based therapy." in: Cancer research, Vol. 72, Issue 21, pp. 5556-65, (2012) (PubMed).
: "CD22 regulates adaptive and innate immune responses of B cells." in: Journal of innate immunity, Vol. 3, Issue 4, pp. 411-9, (2011) (PubMed).
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: "CD22 antigen is broadly expressed on lung cancer cells and is a target for antibody-based therapy." in: Cancer research, Vol. 72, Issue 21, pp. 5556-65, (2012) (PubMed).
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- Target
- CD22 (CD22 Molecule (CD22))
- Andere Bezeichnung
- CD22 (CD22 Produkte)
- Synonyme
- A530093D23 antikoerper, Lyb-8 antikoerper, Lyb8 antikoerper, SIGLEC-2 antikoerper, SIGLEC2 antikoerper, siglec-2 antikoerper, CD22 antigen antikoerper, CD22 molecule antikoerper, Cd22 antikoerper, CD22 antikoerper
- Hintergrund
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Description: CD22 may be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins, one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules ,
Aliases: SIGLEC2, SIGLEC-2
- Molekulargewicht
- 95.3 kDa
- Gen-ID
- 933
- HGNC
- 933
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