RING1 Antikörper (AA 79-263)

Produktnummer ABIN1724897

Produktdetails anti-RING1 Antikörper

Target: RING1 (Ring Finger Protein 1 (RING1))

Bindungsspezifität: AA 79-263

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RING1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunocytochemistry (ICC)

Verwendungszweck: Ring1 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human Ring1 (AA: 79-263) expressed in E. Coli.

Klon: 8E8A2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-RING1 Antikörper (ABIN1724897)

Vidal: "Role of polycomb proteins Ring1A and Ring1B in the epigenetic regulation of gene expression." in: The International journal of developmental biology, Vol. 53, Issue 2-3, pp. 355-70, (2009) (PubMed).

Details zu RING1

Target: RING1 (Ring Finger Protein 1 (RING1))

Andere Bezeichnung: Ring1 (RING1 Produkte)

Synonyme: RING1A antikoerper, RNF1 antikoerper, Ring1A antikoerper, bap-1 antikoerper, bap1 antikoerper, ding antikoerper, hipi3 antikoerper, ring1a antikoerper, ring1b antikoerper, ring2 antikoerper, rnf1 antikoerper, rnf2-a antikoerper, ring1 antikoerper, ring1b-B antikoerper, rnf2-b antikoerper, ring finger protein 1 antikoerper, ring finger protein 1 S homeolog antikoerper, ring finger protein 1 L homeolog antikoerper, RING1 antikoerper, Ring1 antikoerper, ring1.S antikoerper, ring1.L antikoerper

Hintergrund:

Description: This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.

Aliases: RNF1, RING1A

Molekulargewicht: 42.4kDa

Gen-ID: 6015

HGNC: 6015

UniProt: Q06587