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DIS3L2 Antikörper (AA 27-250)

DIS3L2 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Maus Monoclonal 6C7B2 unconjugated
Produktnummer ABIN1724900
  • Target Alle DIS3L2 Antikörper anzeigen
    DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))
    Bindungsspezifität
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 27-250
    Reaktivität
    • 36
    • 20
    • 20
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 28
    • 8
    • 1
    Maus
    Klonalität
    • 30
    • 7
    Monoklonal
    Konjugat
    • 12
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DIS3L2 Antikörper ist unkonjugiert
    Applikation
    • 25
    • 13
    • 6
    • 6
    • 5
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Verwendungszweck
    DIS3L2 Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human DIS3L2 (AA: 27-250) expressed in E. Coli.
    Klon
    6C7B2
    Isotyp
    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Du Toit: "Cytoskeleton: Formins induce nuclear actin assembly." in: Nature reviews. Molecular cell biology, Vol. 14, Issue 6, pp. 328, (2013) (PubMed).

    Astuti, Morris, Cooper, Staals, Wake, Fews, Gill, Gentle, Shuib, Ricketts, Cole, van Essen, van Lingen, Neri, Opitz, Rump, Stolte-Dijkstra, Müller, Pruijn, Latif, Maher: "Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility." in: Nature genetics, Vol. 44, Issue 3, pp. 277-84, (2012) (PubMed).

  • Target
    DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))
    Andere Bezeichnung
    DIS3L2 (DIS3L2 Produkte)
    Synonyme
    RGD1560168 antikoerper, DIS3L2 antikoerper, DKFZp469O0522 antikoerper, FAM6A antikoerper, PRLMNS antikoerper, hDIS3L2 antikoerper, 4930429A22Rik antikoerper, 8030493P09Rik antikoerper, DIS3-like 3'-5' exoribonuclease 2 antikoerper, DIS3 like 3'-5' exoribonuclease 2 antikoerper, DIS3-like exonuclease 2 antikoerper, Dis3l2 antikoerper, DIS3L2 antikoerper, LOC100344728 antikoerper
    Hintergrund

    Description: The protein encoded by this gene is similar in sequence to 3'/5' exonucleolytic subunits of the RNA exosome. The exosome is a large multimeric ribonucleotide complex responsible for degrading various RNA substrates. Several transcript variants, some protein-coding and some not, have been found for this gene.

    Aliases: FAM6A, PRLMNS

    Molekulargewicht
    99.3kDa
    Gen-ID
    129563
    HGNC
    129563
    UniProt
    Q8IYB7
    Pathways
    Stem Cell Maintenance
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