IGFBP7 Antikörper (AA 52-156)

Produktnummer ABIN1724903

Produktdetails anti-IGFBP7 Antikörper

Target: IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

Bindungsspezifität: AA 52-156

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IGFBP7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human IGFBP7 (AA: 52-156) expressed in E. coli.

Klon: 1D9E7

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-IGFBP7 Antikörper (ABIN1724903)

Evdokimova, Tognon, Benatar, Yang, Krutikov, Pollak, Sorensen, Seth: "IGFBP7 binds to the IGF-1 receptor and blocks its activation by insulin-like growth factors." in: Science signaling, Vol. 5, Issue 255, pp. ra92, (2012) (PubMed).

Details zu IGFBP7

Target: IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

Andere Bezeichnung: IGFBP7 (IGFBP7 Produkte)

Synonyme: zgc:85888 antikoerper, AGM antikoerper, FSTL2 antikoerper, IBP-7 antikoerper, IGFBP-7 antikoerper, IGFBP-7v antikoerper, IGFBPRP1 antikoerper, MAC25 antikoerper, PSF antikoerper, RAMSVPS antikoerper, TAF antikoerper, Fstl2 antikoerper, Mac25 antikoerper, insulin like growth factor binding protein 7 antikoerper, insulin-like growth factor binding protein 7 antikoerper, IGFBP7 antikoerper, igfbp7 antikoerper, Igfbp7 antikoerper

Hintergrund:

Description: This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). ,

Aliases: AGM, PSF, TAF, FSTL2, IBP-7, MAC25, IGFBP-7, RAMSVPS, IGFBP-7v, IGFBPRP1

Molekulargewicht: 29.1 kDa

Gen-ID: 3490

HGNC: 3490

Pathways: Growth Factor Binding