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Dynamin 1-Like Antikörper (AA 69-213)

DNM1L Reaktivität: Human WB, ELISA, ICC, FACS Wirt: Maus Monoclonal 4A4C7 unconjugated
Produktnummer ABIN1724907
  • Target Alle Dynamin 1-Like (DNM1L) Antikörper anzeigen
    Dynamin 1-Like (DNM1L)
    Bindungsspezifität
    • 23
    • 11
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 69-213
    Reaktivität
    • 51
    • 45
    • 28
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 59
    • 7
    Maus
    Klonalität
    • 59
    • 7
    Monoklonal
    Konjugat
    • 32
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Dynamin 1-Like Antikörper ist unkonjugiert
    Applikation
    • 33
    • 27
    • 18
    • 13
    • 13
    • 12
    • 9
    • 8
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Verwendungszweck
    DNM1L Antibody
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human DNM1L (AA: 69-213) expressed in E. Coli.
    Klon
    4A4C7
    Isotyp
    IgG1
    Top Product
    Discover our top product DNM1L Primärantikörper
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Thomas, Jacobson: "Defects in mitochondrial fission protein dynamin-related protein 1 are linked to apoptotic resistance and autophagy in a lung cancer model." in: PLoS ONE, Vol. 7, Issue 9, pp. e45319, (2012) (PubMed).

    Marsboom, Toth, Ryan, Hong, Wu, Fang, Thenappan, Piao, Zhang, Pogoriler, Chen, Morrow, Weir, Rehman, Archer: "Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension." in: Circulation research, Vol. 110, Issue 11, pp. 1484-97, (2012) (PubMed).

  • Target
    Dynamin 1-Like (DNM1L)
    Andere Bezeichnung
    DNM1L (DNM1L Produkte)
    Hintergrund

    Description: The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated.

    Aliases: DLP1, DRP1, DVLP, EMPF, VPS1, DYMPLE, HDYNIV, DYNIV-11

    Molekulargewicht
    81.9kDa
    Gen-ID
    10059
    HGNC
    10059
    UniProt
    O00429
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