SOX10 Antikörper (AA 147-252)

Produktnummer ABIN1724912

Produktdetails anti-SOX10 Antikörper

Target: SOX10 (SRY (Sex Determining Region Y)-Box 10 (SOX10))

Bindungsspezifität: AA 147-252

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SOX10 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Verwendungszweck: SOX10 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human SOX10 (AA: 147-252) expressed in E. Coli.

Klon: 2E7E8

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-SOX10 Antikörper (ABIN1724912)

Shin, Vincent, Cuda, Xu, Kang, Kim, Taube: "Sox10 is expressed in primary melanocytic neoplasms of various histologies but not in fibrohistiocytic proliferations and histiocytoses." in: Journal of the American Academy of Dermatology, Vol. 67, Issue 4, pp. 717-26, (2012) (PubMed).

Bannykh, Stolt, Kim, Perry, Wegner: "Oligodendroglial-specific transcriptional factor SOX10 is ubiquitously expressed in human gliomas." in: Journal of neuro-oncology, Vol. 76, Issue 2, pp. 115-27, (2006) (PubMed).

Details zu SOX10

Target: SOX10 (SRY (Sex Determining Region Y)-Box 10 (SOX10))

Andere Bezeichnung: SOX10 (SOX10 Produkte)

Synonyme: DOM antikoerper, PCWH antikoerper, WS2E antikoerper, WS4 antikoerper, WS4C antikoerper, SOX-10 antikoerper, SOX10 antikoerper, dom antikoerper, ws4 antikoerper, Dom antikoerper, Sox21 antikoerper, SOX9 antikoerper, cls/sox10 antikoerper, zgc:100757 antikoerper, SRY-box 10 antikoerper, SRY box 10 antikoerper, SRY-box 10 L homeolog antikoerper, SRY (sex determining region Y)-box 10 antikoerper, SOX10 antikoerper, Sox10 antikoerper, sox10.L antikoerper, sox10 antikoerper

Hintergrund:

Description: This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.

Aliases: DOM, WS4, PCWH, WS2E, WS4C

Molekulargewicht: 49.9kDa

Gen-ID: 6663

HGNC: 6663

UniProt: P56693

Pathways: Chromatin Binding