DARPP32 Antikörper (AA 95-204)
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- Target Alle DARPP32 (PPP1R1B) Antikörper anzeigen
- DARPP32 (PPP1R1B) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B))
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Bindungsspezifität
- AA 95-204
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser DARPP32 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human PPP1R1B (AA: 95-204) expressed in E. coli.
- Klon
- 2G6D9
- Isotyp
- IgG1
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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Detailed DARPP-32 expression profiles in postmortem brains from patients with schizophrenia: an immunohistochemical study." in: Medical molecular morphology, Vol. 44, Issue 4, pp. 190-9, (2011) (PubMed).
: "Both t-Darpp and DARPP-32 can cause resistance to trastuzumab in breast cancer cells and are frequently expressed in primary breast cancers." in: Breast cancer research and treatment, Vol. 120, Issue 1, pp. 47-57, (2010) (PubMed).
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Detailed DARPP-32 expression profiles in postmortem brains from patients with schizophrenia: an immunohistochemical study." in: Medical molecular morphology, Vol. 44, Issue 4, pp. 190-9, (2011) (PubMed).
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- Target
- DARPP32 (PPP1R1B) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B))
- Andere Bezeichnung
- PPP1R1B (PPP1R1B Produkte)
- Synonyme
- darpp32 antikoerper, darpp-32 antikoerper, Darpp-32 antikoerper, Darpp32 antikoerper, DARPP-32 antikoerper, DARPP32 antikoerper, AU040756 antikoerper, protein phosphatase 1 regulatory inhibitor subunit 1B antikoerper, protein phosphatase 1, regulatory (inhibitor) subunit 1B antikoerper, protein phosphatase 1 regulatory inhibitor subunit 1B S homeolog antikoerper, ppp1r1b antikoerper, PPP1R1B antikoerper, Ppp1r1b antikoerper, ppp1r1b.S antikoerper
- Hintergrund
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Description: This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. ,
Aliases: DARPP32, DARPP-32
- Molekulargewicht
- 23 kDa
- Gen-ID
- 84152
- HGNC
- 84152
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