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beta-2 Microglobulin Antikörper (AA 21-100)

B2M Reaktivität: Human WB, FACS, ELISA, IHC Wirt: Maus Monoclonal 3G5H8 unconjugated
Produktnummer ABIN1724930
  • Target Alle beta-2 Microglobulin (B2M) Antikörper anzeigen
    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
    Bindungsspezifität
    • 19
    • 17
    • 15
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-100
    Reaktivität
    • 209
    • 52
    • 30
    • 27
    • 10
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 123
    • 116
    • 9
    • 6
    • 2
    • 1
    Maus
    Klonalität
    • 131
    • 125
    • 1
    Monoklonal
    Konjugat
    • 113
    • 32
    • 26
    • 14
    • 13
    • 8
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser beta-2 Microglobulin Antikörper ist unkonjugiert
    Applikation
    • 128
    • 110
    • 75
    • 66
    • 60
    • 41
    • 40
    • 31
    • 26
    • 18
    • 17
    • 15
    • 13
    • 12
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC)
    Verwendungszweck
    B2M Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human B2M (AA: 21-100) expressed in E. Coli.
    Klon
    3G5H8
    Isotyp
    IgG2a
    Top Product
    Discover our top product B2M Primärantikörper
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Bernal, Ruiz-Cabello, Concha, Paschen, Garrido: "Implication of the ?2-microglobulin gene in the generation of tumor escape phenotypes." in: Cancer immunology, immunotherapy : CII, Vol. 61, Issue 9, pp. 1359-71, (2012) (PubMed).

    Hermansen, Hummelshøj, Lundsgaard, Hornum, Keller, Fleckner, Fox, Poulsen, Jacobsen: "Increased serum ?2-microglobulin is associated with clinical and immunological markers of disease activity in systemic lupus erythematosus patients." in: Lupus, Vol. 21, Issue 10, pp. 1098-104, (2012) (PubMed).

  • Target
    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
    Andere Bezeichnung
    B2M (B2M Produkte)
    Synonyme
    Ly-m11 antikoerper, beta2-m antikoerper, beta2m antikoerper, bwm antikoerper, wu:fa94c05 antikoerper, wu:fb10a09 antikoerper, b2m-W01 antikoerper, b2m-W03 antikoerper, b2m-Z01 antikoerper, b2m-Z02 antikoerper, b2m-Z03 antikoerper, B2M antikoerper, b2m antikoerper, B2MG antikoerper, wu:fb66f11 antikoerper, wu:fj01f08 antikoerper, zgc:64161 antikoerper, b-2-m antikoerper, beta-2-microglobulin antikoerper, beta-2 microglobulin antikoerper, beta-2-microglobulin S homeolog antikoerper, beta-2-microglobulin, like antikoerper, B2M antikoerper, B2m antikoerper, b2m antikoerper, b2m.S antikoerper, b2ml antikoerper
    Hintergrund
    This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
    Molekulargewicht
    13.7kDa
    Gen-ID
    567
    HGNC
    567
    UniProt
    P61769
    Pathways
    T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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