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Syndecan 1 Antikörper (AA 28-171)

Name: Syndecan 1 Antikörper (AA 28-171)
Brand: antibodies-online
SKU: ABIN1724936
Price: 640.59 EUR
Availability: InStock

SDC1 Reaktivität: Human WB, ELISA, FACS, IHC, ICC Wirt: Maus Monoclonal 1A3H4 unconjugated

Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using SDC1 mouse mAb with DAB staining. (Syndecan 1 Antikörper (AA 28-171))

IHC

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (Syndecan 1 Antikörper (AA 28-171))

ELISA

Flow cytometric analysis of HepG2 cells using SDC1 mouse mAb (green) and negative control (red). (Syndecan 1 Antikörper (AA 28-171))

FACS

Immunofluorescence analysis of HepG2 cells using SDC1 mouse mAb (green). (Syndecan 1 Antikörper (AA 28-171))

Western blot analysis using SDC1 mouse mAb against MCF-7 (1), Hela (2), HepG2 (3), T47D (4), SW620 (5), Jurkat (6) and NIH/3T3 (7) cell lysate. (Syndecan 1 Antikörper (AA 28-171))

Western blot analysis using SDC1 mAb against human SDC1 (AA: 28-171) recombinant protein. (Syndecan 1 Antikörper (AA 28-171))

Western blot analysis using SDC1 mAb against HEK293 (1) and SDC1 (AA: 28-171)-hIgGFc transfected HEK293 (2) cell lysate. (Syndecan 1 Antikörper (AA 28-171))

Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using SDC1 mouse mAb with DAB staining. (Syndecan 1 Antikörper (AA 28-171))

IHC

8 Abbildungen

(2 Referenzen)

Produktnummer ABIN1724936

Datenblatt (PDF)

Target Alle Syndecan 1 (SDC1) Antikörper anzeigen

Syndecan 1 (SDC1)
Bindungsspezifität
16

8

8

5

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 28-171
Reaktivität
114

44

40

17

5
Human
Wirt
73

45

10

1
Maus
Passende Sekundärantikörper
Klonalität
67

62
Monoklonal
Konjugat
55

13

9

9

9

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Dieser Syndecan 1 Antikörper ist unkonjugiert
Applikation
66

46

40

25

14

13

13

11

11

11

9

3

3

2

2

2

1

1

1

1

1
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Verwendungszweck

SDC1 Antibody

Aufreinigung

Purified antibody

Immunogen

Purified recombinant fragment of human SDC1 (AA: 28-171) expressed in E. Coli.

Klon

1A3H4

Isotyp

IgG1

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Applikationshinweise

ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Nunez, Siegal, Reddy, Wei: "CD138 (syndecan-1) expression in bone-forming tumors." in: American journal of clinical pathology, Vol. 137, Issue 3, pp. 423-8, (2012) (PubMed).

Karasneh, Ali, Shukla: "An important role for syndecan-1 in herpes simplex virus type-1 induced cell-to-cell fusion and virus spread." in: PLoS ONE, Vol. 6, Issue 9, pp. e25252, (2011) (PubMed).
Target

Syndecan 1 (SDC1)

Andere Bezeichnung

SDC1 (SDC1 Produkte)

Hintergrund

Description: The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.

Aliases: SDC, CD138, SYND1, syndecan

Molekulargewicht

32.5kDa

Gen-ID

6382

HGNC

6382

UniProt

P18827

Pathways

Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism