Syndecan 1 Antikörper (AA 28-171)

Produktnummer ABIN1724936

Produktdetails anti-Syndecan 1 Antikörper

Target: Syndecan 1 (SDC1)

Bindungsspezifität: AA 28-171

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Syndecan 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Verwendungszweck: SDC1 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human SDC1 (AA: 28-171) expressed in E. Coli.

Klon: 1A3H4

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-Syndecan 1 Antikörper (ABIN1724936)

Nunez, Siegal, Reddy, Wei: "CD138 (syndecan-1) expression in bone-forming tumors." in: American journal of clinical pathology, Vol. 137, Issue 3, pp. 423-8, (2012) (PubMed).

Karasneh, Ali, Shukla: "An important role for syndecan-1 in herpes simplex virus type-1 induced cell-to-cell fusion and virus spread." in: PLoS ONE, Vol. 6, Issue 9, pp. e25252, (2011) (PubMed).

Details zu Syndecan 1

Target: Syndecan 1 (SDC1)

Andere Bezeichnung: SDC1 (SDC1 Produkte)

Synonyme: CG10497 antikoerper, CT27296 antikoerper, Dmel\\CG10497 antikoerper, Dsyn antikoerper, Syd antikoerper, Syn antikoerper, dSdc antikoerper, l(2)10608 antikoerper, sdc antikoerper, syd antikoerper, syn antikoerper, Syn1 antikoerper, cd138 antikoerper, synd1 antikoerper, xSyn1 antikoerper, syndecan1 antikoerper, Syndecan-1 antikoerper, XSyndecan-1 antikoerper, SDC1 antikoerper, CD138 antikoerper, SDC antikoerper, SYND1 antikoerper, syndecan antikoerper, AA408134 antikoerper, AA409076 antikoerper, Sstn antikoerper, Synd antikoerper, Synd1 antikoerper, syn-1 antikoerper, HSPG antikoerper, SYNDECA antikoerper, Syndecan antikoerper, Syndecan antikoerper, syndecan 1 antikoerper, Sdc antikoerper, sdc1 antikoerper, SDC1 antikoerper, Sdc1 antikoerper

Hintergrund:

Description: The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.

Aliases: SDC, CD138, SYND1, syndecan

Molekulargewicht: 32.5kDa

Gen-ID: 6382

HGNC: 6382

UniProt: P18827

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism