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GABBR2 Antikörper (AA 319-483)

GABBR2 Reaktivität: Human IHC, ELISA, ICC Wirt: Maus Monoclonal 5G7F7 unconjugated
Produktnummer ABIN1724937
  • Target Alle GABBR2 Antikörper anzeigen
    GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
    Bindungsspezifität
    • 19
    • 15
    • 15
    • 15
    • 12
    • 8
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 319-483
    Reaktivität
    • 83
    • 64
    • 58
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 99
    • 15
    Maus
    Klonalität
    • 91
    • 23
    Monoklonal
    Konjugat
    • 33
    • 9
    • 8
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GABBR2 Antikörper ist unkonjugiert
    Applikation
    • 106
    • 52
    • 52
    • 32
    • 27
    • 16
    • 15
    • 13
    • 12
    • 6
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
    Verwendungszweck
    GABBR2 Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human GABBR2 (AA: 319-483) expressed in E. Coli.
    Klon
    5G7F7
    Isotyp
    IgG2a
  • Applikationshinweise

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Balasubramanian, Fam, Hall: "GABAB receptor association with the PDZ scaffold Mupp1 alters receptor stability and function." in: The Journal of biological chemistry, Vol. 282, Issue 6, pp. 4162-71, (2007) (PubMed).

  • Target
    GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
    Andere Bezeichnung
    GABBR2 (GABBR2 Produkte)
    Hintergrund

    Description: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.



    Aliases: HG20, GPR51, GPRC3B, GABABR2, HRIHFB2099

    Molekulargewicht
    105.8kDa
    Gen-ID
    9568
    HGNC
    9568
    UniProt
    O75899
    Pathways
    cAMP Metabolic Process
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