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TRF2 Antikörper (AA 324-500)

TERF2 Reaktivität: Human ELISA, IHC Wirt: Maus Monoclonal 3H6B4 unconjugated
Produktnummer ABIN1724941
  • Target Alle TRF2 (TERF2) Antikörper anzeigen
    TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))
    Bindungsspezifität
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 324-500
    Reaktivität
    • 39
    • 10
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 34
    • 4
    • 2
    Maus
    Klonalität
    • 37
    • 3
    Monoklonal
    Konjugat
    • 22
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TRF2 Antikörper ist unkonjugiert
    Applikation
    • 29
    • 20
    • 18
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Verwendungszweck
    TERF2 Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human TERF2 (AA: 324-500) expressed in E. Coli.
    Klon
    3H6B4
    Isotyp
    IgG1
  • Applikationshinweise
    ELISA: 1/10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Galati, Magdinier, Colasanti, Bauwens, Pinte, Ricordy, Giraud-Panis, Pusch, Savino, Cacchione, Gilson: "TRF2 controls telomeric nucleosome organization in a cell cycle phase-dependent manner." in: PLoS ONE, Vol. 7, Issue 4, pp. e34386, (2012) (PubMed).

    Diehl, Idowu, Kimmelshue, York, Jackson-Cook, Turner, Holt, Elmore: "Elevated TRF2 in advanced breast cancers with short telomeres." in: Breast cancer research and treatment, Vol. 127, Issue 3, pp. 623-30, (2011) (PubMed).

  • Target
    TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))
    Andere Bezeichnung
    TERF2 (TERF2 Produkte)
    Synonyme
    TERF2 antikoerper, TRBF2 antikoerper, TRF2 antikoerper, trf2 antikoerper, telomeric repeat binding factor 2 antikoerper, telomeric repeat binding factor 2 L homeolog antikoerper, TERF2 antikoerper, Terf2 antikoerper, terf2.L antikoerper
    Hintergrund

    Description: This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.


    Aliases: TRF2, TRBF2

    Molekulargewicht
    55.6kDa
    Gen-ID
    7014
    HGNC
    7014
    UniProt
    Q15554
    Pathways
    Zellzyklus, Telomere Maintenance
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