TRF2 Antikörper (AA 324-500)
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- Target Alle TRF2 (TERF2) Antikörper anzeigen
- TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))
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Bindungsspezifität
- AA 324-500
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser TRF2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human TERF2 (AA: 324-500) expressed in E. coli.
- Klon
- 3H6B4
- Isotyp
- IgG1
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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TRF2 controls telomeric nucleosome organization in a cell cycle phase-dependent manner." in: PLoS ONE, Vol. 7, Issue 4, pp. e34386, (2012) (PubMed).
: "Elevated TRF2 in advanced breast cancers with short telomeres." in: Breast cancer research and treatment, Vol. 127, Issue 3, pp. 623-30, (2011) (PubMed).
: "
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TRF2 controls telomeric nucleosome organization in a cell cycle phase-dependent manner." in: PLoS ONE, Vol. 7, Issue 4, pp. e34386, (2012) (PubMed).
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- Target
- TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))
- Andere Bezeichnung
- TERF2 (TERF2 Produkte)
- Synonyme
- TERF2 antikoerper, TRBF2 antikoerper, TRF2 antikoerper, trf2 antikoerper, telomeric repeat binding factor 2 antikoerper, telomeric repeat binding factor 2 L homeolog antikoerper, TERF2 antikoerper, Terf2 antikoerper, terf2.L antikoerper
- Hintergrund
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Description: This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. , , ,
Aliases: TRF2, TRBF2
- Molekulargewicht
- 55.6 kDa
- Gen-ID
- 7014
- HGNC
- 7014
- Pathways
- Zellzyklus, Telomere Maintenance
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