Axin Antikörper (C-Term)
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- Target Alle Axin (AXIN1) Antikörper anzeigen
- Axin (AXIN1) (Axin 1 (AXIN1))
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Bindungsspezifität
- C-Term
- Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund
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Wirt
- Ziege
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Klonalität
- Polyklonal
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Konjugat
- Dieser Axin Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- Reacts with the C-terminus part of human AXIN1
- Kreuzreaktivität
- Maus, Rind (Kuh), Hund, Ratte (Rattus)
- Kreuzreaktivität (Details)
- Cross reacts with bovine, canine, mouse and rat protein. This antibody is expected to recognise both reported isoforms.
- Aufreinigung
- Antigen affinity purified
- Immunogen
- Synthetic peptide C-FEEKIIGKVEKVD from the C-terminus of human AXIN1 (NP_003493.1, NP_851393.1). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Gibbon (100%), Baboon (100%), Monkey (100%), Marmoset (100%)
- Top Product
- Discover our top product AXIN1 Primärantikörper
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- Applikationshinweise
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Working dilution: ELISA (1:128000), IHC-P (3.75 μg/mL)
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/mL
- Buffer
- TBS, pH 7.3, BSA 0.5 % , Sodium azide 0.02 %
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Minimize freezing and thawing.
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- Target
- Axin (AXIN1) (Axin 1 (AXIN1))
- Andere Bezeichnung
- AXIN1 (AXIN1 Produkte)
- Synonyme
- AXIN1 antikoerper, axin antikoerper, fused antikoerper, xAxin antikoerper, LOC100226467 antikoerper, AXIN antikoerper, PPP1R49 antikoerper, AI316800 antikoerper, Axin antikoerper, Fu antikoerper, Kb antikoerper, Ki antikoerper, kinky antikoerper, knobbly antikoerper, AXIN1-RGS antikoerper, wu:fi22e03 antikoerper, wu:fj14c08 antikoerper, wu:fk11b03 antikoerper, zgc:109872 antikoerper, axin 1 antikoerper, axin 1 S homeolog antikoerper, axin 1 L homeolog antikoerper, AXIN1 antikoerper, axin1.S antikoerper, axin1.L antikoerper, Axin1 antikoerper, axin1 antikoerper
- Hintergrund
- Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects, down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway.
- UniProt
- O15169
- Pathways
- WNT Signalweg, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling
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