F12 Antikörper
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- Target Alle F12 Antikörper anzeigen
- F12 (Coagulation Factor XII (F12))
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Reaktivität
- Human
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Wirt
- Ziege
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Klonalität
- Polyklonal
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Konjugat
- Dieser F12 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- Reacts with human F12 / Factor XII
- Kreuzreaktivität (Details)
- Specific for Factor XII as demonstrated by immunodiffusion. A single precipitin arc was obtained with normal plasma and no reaction was observed with F. XII-deficient plasma.
- Aufreinigung
- Purified
- Immunogen
- Activated human Factor XII (F XIIa) purified from plasma.
- Isotyp
- IgG
- Top Product
- Discover our top product F12 Primärantikörper
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- Applikationshinweise
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Working dilution: IHC-P (5 μg/mL)
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- 10 mM HEPES, pH 7.4, 0.15 M NaCl, 50 % glycerol.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Long term: -20°C, Short term: +4°C. Avoid repeat freeze-thaw cycles.
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- Target
- F12 (Coagulation Factor XII (F12))
- Andere Bezeichnung
- F12 / Factor XII (F12 Produkte)
- Hintergrund
- Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa.
- Pathways
- Komplementsystem
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