MGLUR2 + MGLUR3 Antikörper (AA 860-875)

Produktnummer ABIN1736902

Produktdetails anti-MGLUR2 + MGLUR3 Antikörper

Target: MGLUR2 + MGLUR3 (GRM2/3) (Glutamate Receptor, Metabotropic 2/3 (GRM2/3))

Bindungsspezifität: AA 860-875

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MGLUR2 + MGLUR3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Reacts with rat mGluR2/3

Kreuzreaktivität: Maus

Kreuzreaktivität (Details): Predicted react to human and mouse.

Aufreinigung: Purified

Immunogen: Synthetic peptide corresponding to residues 860-875 of the rat mGlurR2/3 protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
-IHC: 1:10-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, Sodium azide 0.02 %

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 6 months

Details zu MGLUR2 + MGLUR3

Target: MGLUR2 + MGLUR3 (GRM2/3) (Glutamate Receptor, Metabotropic 2/3 (GRM2/3))

Andere Bezeichnung: Metabotropic Glutamate Receptor 2/3 (GRM2/3 Produkte)

Hintergrund: Metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors activated by glutamate. Based on sequence similarity, transduction mechanisms and agonist potencies, mGluRs are subdivided into three groups: mGluR1/mGluR5, mGluR2/mGluR3, and mGluR4/mGluR6/mGluR7/mGluR8. mGluRs are widely distributed throughout the nervous system and are expressed by both neurons and glial cells. mGluRs have been suggested to play a variety of functional roles, among which is involvement in synaptic plasticity underlying learning and memory as well as chronic pain.

UniProt: P31421