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GFAP Antikörper (AA 411-422) (APC)

Name: GFAP Antikörper (AA 411-422) (APC)
Brand: antibodies-online
SKU: ABIN1740955
Price: 729.11 EUR
Availability: InStock

GFAP Reaktivität: Human WB, IHC, IF, ICC Wirt: Maus Monoclonal S206A-8 APC

Western Blot analysis of Rat Brain Membrane showing detection of GFAP protein using Mouse Anti-GFAP Monoclonal Antibody, Clone S206A-8 . (GFAP Antikörper (AA 411-422) (APC))

Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-GFAP Monoclonal Antibody, Clone S206A-8 (ABIN1740955). (GFAP Antikörper (AA 411-422) (APC))

ICC

Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-GFAP Monoclonal Antibody, Clone S206A-8 . (GFAP Antikörper (AA 411-422) (APC))

IF/ICC

3 Abbildungen

Produktnummer ABIN1740955

Datenblatt (PDF)

Target Alle GFAP Antikörper anzeigen

GFAP (Glial Fibrillary Acidic Protein (GFAP))
Bindungsspezifität
29

27

26

16

12

9

9

9

8

7

7

6

4

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 411-422
Reaktivität
295

175

174

51

51

34

31

11

11

10

8

6

5

4

3

2

2

2

1

1

1

1

1
Human
Wirt
193

143

12

3

2

2
Maus
Passende Sekundärantikörper
Klonalität
198

157
Monoklonal
Konjugat
167

27

23

16

11

7

6

4

4

4

4

4

4

4

4

4

4

4

4

4

4

4

4

4

4

3

2

2

2

2

2

2

2

2

2

2

1

1

1
Dieser GFAP Antikörper ist konjugiert mit APC
Applikation
271

126

92

79

74

58

47

28

26

26

23

18

13

8

8

4

4

3

2

2

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität

Detects ~50 kDa. Cross-reacts with GFAP-R416W and other GFAP mutant proteins.

Kreuzreaktivität

Human, Maus, Ratte

Aufreinigung

Protein G Purified

Immunogen

Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP, 100% identical in rat and mouse

Klon

S206A-8

Isotyp

IgG1

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anti-Glial Fibrillary Acidic Protein (GFAP) antibody
GFAP Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Monoclonal unconjugated

Applikationshinweise
- WB (1:1000)
- optimal dilutions for assays should be determined by the user.
Kommentare

1 μg/ml of ABIN1740955 was sufficient for detection of GFAP in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C

Informationen zur Lagerung

Conjugated antibodies should be stored at 4°C
Target

GFAP (Glial Fibrillary Acidic Protein (GFAP))

Andere Bezeichnung

GFAP (GFAP Produkte)

Synonyme

GFAP antikoerper, AI836096 antikoerper, cb345 antikoerper, etID36982.3 antikoerper, gfapl antikoerper, wu:fb34h11 antikoerper, wu:fk42c12 antikoerper, xx:af506734 antikoerper, zgc:110485 antikoerper, glial fibrillary acidic protein antikoerper, GFAP antikoerper, LOC100136168 antikoerper, gfap antikoerper, Gfap antikoerper

Hintergrund

The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia.

Gen-ID

2670

NCBI Accession

NP_001124491

UniProt

P14136