PTPRF Antikörper (AA 1315-1607) (FITC)
-
- Target Alle PTPRF Antikörper anzeigen
- PTPRF (Protein Tyrosine Phosphatase Receptor Type F (PTPRF))
-
Bindungsspezifität
- AA 1315-1607
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser PTPRF Antikörper ist konjugiert mit FITC
-
Applikation
- Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Spezifität
- Detects ~85 kDa (full length protein is 210 kDa - smaller due to proteolysis into P-subunit containing transmembrane and intracellular domains.
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Protein G Purified
- Immunogen
- Fusion protein amino acids 1315-1607 (cytoplasmic C-terminus) of human LAR. 97% identical in both rat and mouse. >80% identity with PTPRD and PTPRS. >50% identity with PTPRM and PTPRK.
- Klon
- S165-38
- Isotyp
- IgG2a
- Top Product
- Discover our top product PTPRF Primärantikörper
-
-
- Applikationshinweise
-
- WB (1:1000)
- optimal dilutions for assays should be determined by the user.
- Kommentare
-
1 μg/ml of ABIN1740993 was sufficient for detection of LAR/PTPRF in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Conjugated antibodies should be stored at 4°C
-
- Target
- PTPRF (Protein Tyrosine Phosphatase Receptor Type F (PTPRF))
- Andere Bezeichnung
- LAR (PTPRF Produkte)
- Synonyme
- LAR antikoerper, AA591035 antikoerper, LARS antikoerper, RPTP-LAR antikoerper, LARFN5C antikoerper, zf-LAR antikoerper, protein tyrosine phosphatase, receptor type F antikoerper, protein tyrosine phosphatase, receptor type, F antikoerper, protein tyrosine phosphatase, receptor type, f, a antikoerper, PTPRF antikoerper, Ptprf antikoerper, ptprfa antikoerper
- Hintergrund
- PTPRF or leukocyte common antigen-related protein (LAR) is a widely expressed protein tyrosine phosphatase with an extracellular receptor region that resembles a cell adhesion molecule. PTPRF removes phosphate group from β-catenin, an event that may subsequently facilitate cell-cell adhesion and ensure the stability of the cadherin complex. This phosphatase has also been implicated in various cellular processes such as neurite growth, nerve regeneration, actin remodeling and regulation of insulin function (1,2,3,4). Anti-PTPRF (C-terminal) antibody is specific for the extracellular and cytoplasmic subunits of human PTPRF (approx. 210, 150 and 85 kDa). Detection of the PTPRF bands by immunoblotting is specifically inhibited by the immunizing peptide.
- Gen-ID
- 5792
- UniProt
- P10586
- Pathways
- EGFR Signaling Pathway
-