MFN2 Antikörper (AA 370-600) (Biotin)
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- Target Alle MFN2 Antikörper anzeigen
- MFN2 (Mitofusin 2 (MFN2))
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Bindungsspezifität
- AA 370-600
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser MFN2 Antikörper ist konjugiert mit Biotin
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Spezifität
- Detects ~90 kDa. No cross-reactivity against Mitofusin-1.
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Protein G Purified
- Immunogen
- Fusion protein amino acids 370-600 (cytoplasmic N-terminus) of mouse Mitofusin-2. Rat: 97% identity (226/231 amino acids identical). Human: 92% identity (214/231 amino acids identical) ~55% identity with Mitofusin-1.
- Klon
- S153-5
- Isotyp
- IgG2a
- Top Product
- Discover our top product MFN2 Primärantikörper
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anti-Mitofusin 2 (MFN2) (AA 661-757) antibody
MFN2 Reaktivität: Human WB, ELISA, IHC (p), RNAi Wirt: Maus Monoclonal 4H8 unconjugated
anti-Mitofusin 2 (MFN2) (AA 1-120) antibodyMFN2 Reaktivität: Human, Ratte, Maus, Kaninchen WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 500-600) antibodyMFN2 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 447-476) antibodyMFN2 Reaktivität: Human, Maus WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB21136 unconjugated
anti-Mitofusin 2 (MFN2) (AA 687-757) antibodyMFN2 Reaktivität: Maus WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 447-476) antibodyMFN2 Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (N-Term) antibodyMFN2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 370-600) antibodyMFN2 Reaktivität: Human WB, IHC, ICC, IF Wirt: Maus Monoclonal S153-5 unconjugated
anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (Alkaline Phosphatase (AP))MFN2 Reaktivität: Human WB, IHC, ICC, IF Wirt: Maus Monoclonal S153-5 Alkaline Phosphatase (AP)
anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (HRP)MFN2 Reaktivität: Human WB, IHC, ICC, IF Wirt: Maus Monoclonal S153-5 HRP
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- Applikationshinweise
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- Kommentare
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1 μg/ml of ABIN1741244 was sufficient for detection of Mitofusin-2 in 20 μg of mouse cardiac mitochondrial lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Conjugated antibodies should be stored at 4°C
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- Target
- MFN2 (Mitofusin 2 (MFN2))
- Andere Bezeichnung
- Mitofusin 2 (MFN2 Produkte)
- Hintergrund
- Mitofusin-2 (Mfn2) is a membrane protein of the mitochondria and is important in mitochondrial fusion in mammalian cells. Mfn2 activity has also been implicated in mitochondrial metabolism and the loss of Mfn2 may be the reason for certain metabolic modifications that are seen in individuals with obesity. Mfn2 has been associated with maintaining the membrane potential of the mitochondria. Mfn2 has been shown to hinder mitochondrial antiviral signaling by inhibiting production of type 1 interferons. Mfn2 is a p53-inducible target and involved in cell proliferation, apoptosis promotion and tumor suppression.
- Gen-ID
- 170731
- NCBI Accession
- NP_573464
- UniProt
- Q80U63
- Pathways
- Skeletal Muscle Fiber Development
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