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QKI Antikörper (AA 1-341) (Atto 488)

QKI Reaktivität: Human WB, IHC, IF, ICC Wirt: Maus Monoclonal S147-6 Atto 488
Produktnummer ABIN1741379
  • Target Alle QKI Antikörper anzeigen
    QKI (Protein Quaking (QKI))
    Bindungsspezifität
    • 21
    • 11
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-341
    Reaktivität
    • 53
    • 15
    • 11
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 30
    • 25
    • 1
    Maus
    Klonalität
    • 31
    • 25
    Monoklonal
    Konjugat
    • 30
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser QKI Antikörper ist konjugiert mit Atto 488
    Applikation
    • 53
    • 40
    • 25
    • 21
    • 14
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    Detects ~36-38 kDa.
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Protein G Purified
    Immunogen
    Fusion protein amino acids 1-341 (full-length) of human QKI-5. Mouse: 100% identity (341/341 amino acids identical). Rat: 99% identity (339/341 amino acids identical) >90% identity with QKI-6, QKI-7 and QKI-7b.
    Klon
    S147-6
    Isotyp
    IgG2b
    Top Product
    Discover our top product QKI Primärantikörper
  • Applikationshinweise
    • WB (1:1000)
    • optimal dilutions for assays should be determined by the user.
    Kommentare

    1 μg/ml of ABIN1741379 was sufficient for detection of Pan-QKI in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Conjugated antibodies should be stored at 4°C
  • Target
    QKI (Protein Quaking (QKI))
    Andere Bezeichnung
    QKI (QKI Produkte)
    Synonyme
    Hqk antikoerper, QK antikoerper, QK1 antikoerper, QK3 antikoerper, hqkI antikoerper, 1110003F05Rik antikoerper, 1500005P18 antikoerper, QkI antikoerper, l(17)-1Wis antikoerper, l17Wis1 antikoerper, Qki antikoerper, CQKI antikoerper, QKI-5 antikoerper, PqkI antikoerper, BqkI antikoerper, qk antikoerper, qk1 antikoerper, quaking antikoerper, Xqua antikoerper, qki antikoerper, EQKI antikoerper, EqkI antikoerper, QKI, KH domain containing RNA binding antikoerper, quaking antikoerper, QKI, KH domain containing, RNA binding S homeolog antikoerper, QKI, KH domain containing, RNA binding L homeolog antikoerper, QKI antikoerper, Qk antikoerper, qki.S antikoerper, qki.L antikoerper, Qki antikoerper
    Hintergrund
    QKI is also called Protein Quaking or HqkI. QKI is an RNA-binding protein that plays a central role in myelinization. QKI acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation, and is itself, regulated by alternative splicing. QKI is expressed in the frontal cortex of brain, but is shown to be down-regulated in the brain of schizophrenic patients.
    Gen-ID
    9444
    UniProt
    Q96PU8
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