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Neuroligin 3 Antikörper (AA 730-848)

NLGN3 Reaktivität: Ratte WB, IHC, ICC, IF Wirt: Maus Monoclonal S110-29 unconjugated
Produktnummer ABIN1741449
  • Target Alle Neuroligin 3 (NLGN3) Antikörper anzeigen
    Neuroligin 3 (NLGN3)
    Bindungsspezifität
    • 19
    • 15
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 730-848
    Reaktivität
    • 35
    • 33
    • 27
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Ratte
    Wirt
    • 38
    • 26
    • 1
    • 1
    Maus
    Klonalität
    • 43
    • 23
    Monoklonal
    Konjugat
    • 25
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Neuroligin 3 Antikörper ist unkonjugiert
    Applikation
    • 38
    • 22
    • 22
    • 13
    • 13
    • 11
    • 11
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Spezifität
    Detects ~110 kDa. Does not cross-react with Neuroligin-1, -2, -4 or -4.
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Protein G Purified
    Immunogen
    Fusion protein amino acids 730-848 (intracellular C-terminus) of rat Neuroligin-3. Mouse: 99% identity (118/119 amino acids identical). Human: 98% identity (116/119 amino acids identical) ~60% identity with Neuroligin-1. ~40% identity with Neuroligin-2.
    Klon
    S110-29
    Isotyp
    IgG1
  • Applikationshinweise
    • WB (1:1000)
    • optimal dilutions for assays should be determined by the user.
    Kommentare

    1 μg/ml of ABIN1741449 was sufficient for detection of Neuroligin 3 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C
  • Target
    Neuroligin 3 (NLGN3)
    Andere Bezeichnung
    Neuroligin 3 (NLGN3 Produkte)
    Synonyme
    Nlgn3 antikoerper, GB18290 antikoerper, hnl3 antikoerper, NLGN3 antikoerper, CCE-L1 antikoerper, NV16744 antikoerper, Nv1604741 antikoerper, HNL3 antikoerper, A230085M13Rik antikoerper, NL3 antikoerper, neuroligin 3 antikoerper, neuroligin 3 S homeolog antikoerper, NLG-3 antikoerper, nlgn3.S antikoerper, NLGN3 antikoerper, LOC659852 antikoerper, LOC100121155 antikoerper, nlgn3 antikoerper, Nlgn3 antikoerper
    Hintergrund
    Neuroligins are Type I membrane proteins enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities. They have been characterized as neuronal cell surface proteins and are thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. They play a major role in the formation or maintenance of synaptic junctions. They are also thought to be involved in the specification of excitatory synapses. Neuroligins interact with beta-neurexins and this interaction is involved in the formation of functional synapses.
    Gen-ID
    171297
    UniProt
    Q62889
    Pathways
    Synaptic Membrane
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