Neuroligin 3 Antikörper (AA 730-848) (Atto 488)

Produktnummer ABIN1741451

Produktdetails anti-Neuroligin 3 Antikörper (Atto 488)

Target: Neuroligin 3 (NLGN3)

Bindungsspezifität: AA 730-848

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Neuroligin 3 Antikörper ist konjugiert mit Atto 488

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Spezifität: Detects ~110 kDa. Does not cross-react with Neuroligin-1, -2, -4 or -4.

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Protein G Purified

Immunogen: Fusion protein amino acids 730-848 (intracellular C-terminus) of rat Neuroligin-3. Mouse: 99% identity (118/119 amino acids identical). Human: 98% identity (116/119 amino acids identical) ~60% identity with Neuroligin-1. ~40% identity with Neuroligin-2.

Klon: S110-29

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

• WB (1:1000)
• optimal dilutions for assays should be determined by the user.

Kommentare:

1 μg/ml of ABIN1741451 was sufficient for detection of Neuroligin 3 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Conjugated antibodies should be stored at 4°C

Details zu Neuroligin 3

Target: Neuroligin 3 (NLGN3)

Andere Bezeichnung: Neuroligin 3 (NLGN3 Produkte)

Synonyme: Nlgn3 antikoerper, GB18290 antikoerper, hnl3 antikoerper, NLGN3 antikoerper, CCE-L1 antikoerper, NV16744 antikoerper, Nv1604741 antikoerper, HNL3 antikoerper, A230085M13Rik antikoerper, NL3 antikoerper, neuroligin 3 antikoerper, neuroligin 3 S homeolog antikoerper, NLG-3 antikoerper, nlgn3.S antikoerper, NLGN3 antikoerper, LOC659852 antikoerper, LOC100121155 antikoerper, nlgn3 antikoerper, Nlgn3 antikoerper

Hintergrund: Neuroligins are Type I membrane proteins enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities. They have been characterized as neuronal cell surface proteins and are thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. They play a major role in the formation or maintenance of synaptic junctions. They are also thought to be involved in the specification of excitatory synapses. Neuroligins interact with beta-neurexins and this interaction is involved in the formation of functional synapses.

Gen-ID: 171297

UniProt: Q62889

Pathways: Synaptic Membrane