CCR4 Antikörper
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- Target Alle CCR4 Antikörper anzeigen
- CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CCR4 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Cell-ELISA (cELISA)
- Spezifität
- Anti-human CCR4
- Aufreinigung
- Protein G
- Immunogen
- immunisation with human CCR4 peptide
- Klon
- KH-4F5
- Isotyp
- IgG2a
- Top Product
- Discover our top product CCR4 Primärantikörper
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- Applikationshinweise
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Flow cytometry: 1.2 µg/10^6 cells
Immunofluorescence: 1 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. - Kommentare
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Synonyms: CC chemokine receptor 4
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 2 mg/mL
- Buffer
- PBS, pH 7.2
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- short term: 2 °C - 8 °C, long term: -20 °C
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- Target
- CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))
- Andere Bezeichnung
- CCR4 (CCR4 Produkte)
- Synonyme
- CC-CKR-4 antikoerper, CD194 antikoerper, CKR4 antikoerper, CMKBR4 antikoerper, ChemR13 antikoerper, HGCN:14099 antikoerper, K5-5 antikoerper, Ccr4 antikoerper, C-C CKR-4 antikoerper, CHEMR1 antikoerper, Cmkbr4 antikoerper, LESTR antikoerper, Sdf1r antikoerper, C-C motif chemokine receptor 4 antikoerper, chemokine (C-C motif) receptor 4 antikoerper, CCR4 antikoerper, Ccr4 antikoerper
- Hintergrund
- CCR4 (CC chemokine receptor 4) molecule belongs to the rhodopsin family of G-protein-coupled receptors. Chemokine receptors are membrane bound molecules composed of 7-transmembrane domains and coupled to G-proteins. CCR4 binds the chemokines CCL17 (TARC) and CCL22 (MDC) and is highly expressed in most single-positive CD4(+) thymocytes especially in TH2- and regulatory T-cells. It plays a central role in T cell migration to the thymus, T cell maturation and education. CCR4 is often up-regulated in inflammation and cause conformational changes that trigger intracellular signaling pathways.
- UniProt
- P51679
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