EBV Antikörper

Produktnummer ABIN181081

Produktdetails anti-EBV Antikörper

Target: EBV (Epstein-Barr Virus (EBV))

Reaktivität: Epstein-Barr Virus (EBV)

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser EBV Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktmerkmale: Synonyms: HHV4, Epstein Barr Virus LMP2A

Aufreinigung: Affinity Chromatography on Protein G

Immunogen: Bacterial TrpE-LMP2A fusion protein. Spleen cells from immunised Lou/c rats were fusedwith cells of the P3X63. Ag8. 653 myeloma cell line.

Klon: 15F9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/100 - 1/1000. Immunohistochemistry on paraffin sections: This product requires antigen retrieval usingheat treatment methods prior to staining of paraffin sections. Sodium citrate buffer pH 6.0is recommended for this purpose.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu EBV

Target: EBV (Epstein-Barr Virus (EBV))

Andere Bezeichnung: Epstein Barr Virus / EBV (EBV Produkte)

Substanzklasse: Virus

Hintergrund: EBV is a human herpesvirus, which is associated with conditions such as Hodgkins disease and Burkitts Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.Synonyms: HHV-4, HHV4