CD44 Antikörper

Produktnummer ABIN1839614

Produktdetails anti-CD44 Antikörper

Target: CD44

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD44 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: HCAM, CD44 is a transmembrane glycoprotein which is expressed by lymphocytes and several normal epithelial cells. The CD44 Molecule is involved in lymphocyte homing, T-lymphocyte actvitation, interaction with hyaluronic acid and may act as an adhesion molecule. Standard CD 44 (CD44s) is composed of the products of exons 1-5 a less favorable prognosis in gastrointestinal cancers, the loss of CD44s expression predicts unfavorable outcome in bladder cancers, squamous cell carcinomas of the skin, prostatic adenocarcinomas and neuroblastomas. In immunoblotting this antibody reacts with a glycoprotein isolated from hemopoietic cells and epithelials cells with a respective molecular weight of 29-37 and 51 kD.

Immunogen: Isolated CD44 antigen.

Type of Immunogen: Purified protein

Klon: DF 1485

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C.

Details zu CD44

Target: CD44

Andere Bezeichnung: CD44 (CD44 Produkte)

Synonyme: CDW44 antikoerper, CSPG8 antikoerper, ECMR-III antikoerper, HCELL antikoerper, HUTCH-I antikoerper, IN antikoerper, LHR antikoerper, MC56 antikoerper, MDU2 antikoerper, MDU3 antikoerper, MIC4 antikoerper, Pgp1 antikoerper, AU023126 antikoerper, AW121933 antikoerper, AW146109 antikoerper, HERMES antikoerper, Ly-24 antikoerper, Pgp-1 antikoerper, CD44A antikoerper, METAA antikoerper, RHAMM antikoerper, XCD44 antikoerper, cd44 antikoerper, cdw44 antikoerper, cspg8 antikoerper, ecmr-iii antikoerper, hcell antikoerper, lhr antikoerper, mc56 antikoerper, mdu2 antikoerper, mdu3 antikoerper, mic4 antikoerper, mutch-i antikoerper, pgp1 antikoerper, CD44 molecule (Indian blood group) antikoerper, syndecan 4 antikoerper, CD44 antigen antikoerper, CD44 molecule (Indian blood group) S homeolog antikoerper, CD44 antikoerper, SDC4 antikoerper, Cd44 antikoerper, cd44.S antikoerper

Hintergrund: Name/Gene ID: CD44

Synonyms: CD44, CDW44, CD44 antigen, Cell surface glycoprotein CD44, CSPG8, ECMR-III, Epican, HUTCH-I, LHR, MDU2, MC56, MIC4, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, PGP-1, PGP-I, Pgp1, Phagocytic glycoprotein I, MDU3, CD44R, HCELL, Heparan sulfate proteoglycan

Gen-ID: 960

UniProt: P16070

Pathways: Glycosaminoglycan Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling