ACLY Antikörper (AA 306-502)
Kurzübersicht für ACLY Antikörper (AA 306-502) (ABIN1842880)
Target
Alle ACLY Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 306-502
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human ACLY (AA: 306-502) expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.0 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
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- ACLY (ATP Citrate Lyase (ACLY))
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Andere Bezeichnung
- ACLY
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Hintergrund
- ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis.
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Molekulargewicht
- 125 kDa
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Gen-ID
- 47
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UniProt
- P53396
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Pathways
- Warburg Effekt
Target
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