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Doublecortin Antikörper (AA 362-411)

DCX Reaktivität: Human WB, ELISA, IHC, FACS, IF/ICC Wirt: Maus Monoclonal unconjugated
Produktnummer ABIN1844030
  • Target Alle Doublecortin (DCX) Antikörper anzeigen
    Doublecortin (DCX)
    Bindungsspezifität
    • 7
    • 7
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 362-411
    Reaktivität
    • 109
    • 70
    • 65
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 99
    • 12
    • 2
    • 1
    Maus
    Klonalität
    • 95
    • 19
    Monoklonal
    Konjugat
    • 61
    • 9
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Doublecortin Antikörper ist unkonjugiert
    Applikation
    • 73
    • 42
    • 30
    • 13
    • 12
    • 11
    • 8
    • 8
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (fixed cells) (IF/ICC)
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human DCX (AA: 362-411) expressed in E. Coli.
    Isotyp
    IgG1
    Top Product
    Discover our top product DCX Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.0 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
  • Target
    Doublecortin (DCX)
    Andere Bezeichnung
    DCX (DCX Produkte)
    Synonyme
    DCX antikoerper, DBCN antikoerper, DC antikoerper, LISX antikoerper, SCLH antikoerper, XLIS antikoerper, Dbct antikoerper, 18C15.5 antikoerper, doublecortin antikoerper, DCX antikoerper, Dcx antikoerper
    Hintergrund
    In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The protein encoded by this gene is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. The encoded protein contains two doublecortin domains, which bind microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene are a cause of X-linked lissencephaly. Multiple transcript variants encoding at least three different isoforms have been found for this gene.
    Molekulargewicht
    49.3 kDa
    Gen-ID
    1641
    UniProt
    O43602
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