DDB1 Antikörper (C-Term)

Produktnummer ABIN184570

Produktdetails anti-DDB1 Antikörper

Target: DDB1 (Damage Specific DNA Binding Protein 1 (DDB1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser DDB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Verwendungszweck: DDB1

Sequenz: DLIKVVEELT RIH

Kreuzreaktivität: Rind (Kuh), Hund, Human, Maus, Ratte

Aufreinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Güteklasse: Verified

Immunogen: Peptide with sequence C-DLIKVVEELTRIH, from the C Terminus of the protein sequence according to NP_001914.3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry: Paraffin embedded Human Brain (Cortex). Recommended concentration: 4-6 μg/mL.

Western Blot: Approx 140 kDa band observed in lysates of cell line HeLa, HepG2 and Jurkat (calculated MW of 126.9 kDa according to Human NP_001914.3). Recommended concentration: 1-2 μg/mL. Approx 140 kDa band observed in lysates of cell line NIH3T3 and app

Peptide ELISA: antibody detection limit dilution 1:32000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Referenzen für anti-DDB1 Antikörper (ABIN184570)

Li, Robert, van Breugel, Strubin, Zheng: "A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery." in: Nature structural & molecular biology, Vol. 17, Issue 1, pp. 105-11, (2010) (PubMed).

Details zu DDB1

Target: DDB1 (Damage Specific DNA Binding Protein 1 (DDB1))

Andere Bezeichnung: DDB1 (DDB1 Produkte)

Synonyme: DDBA antikoerper, UV-DDB1 antikoerper, XAP1 antikoerper, XPCE antikoerper, XPE antikoerper, XPE-BF antikoerper, DDB1 antikoerper, xpe antikoerper, ddba antikoerper, xap1 antikoerper, xpce antikoerper, xpe-bf antikoerper, uv-ddb1 antikoerper, ddb1 antikoerper, 127kDa antikoerper, AA408517 antikoerper, p127-Ddb1 antikoerper, damage specific DNA binding protein 1 antikoerper, damage-specific DNA binding protein 1, 127kDa antikoerper, DNA damage-binding protein 1 antikoerper, damage-specific DNA binding protein 1 antikoerper, DDB1 antikoerper, ddb1 antikoerper, LOC100187356 antikoerper, Ddb1 antikoerper, ddb-1 antikoerper

Hintergrund: DDB1, damage-specific DNA binding protein 1, 127 kDa, DDBA, XAP1, XPCE, XPE-BF, UV-DDB1, DDB p127 subunit, damage-specific DNA binding protein 1 (127kD), XPE

Gen-ID: 1642, 64470

NCBI Accession: NP_001914

Pathways: DNA Reparatur