Prosaposin Antikörper (AA 325-524)

Produktnummer ABIN1845961

Produktdetails anti-Prosaposin Antikörper

Target: Prosaposin (PSAP)

Bindungsspezifität: AA 325-524

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Prosaposin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (fixed cells) (IF/ICC)

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human PSAP (AA: 325-524) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Details zu Prosaposin

Target: Prosaposin (PSAP)

Andere Bezeichnung: PSAP (PSAP Produkte)

Synonyme: GLBA antikoerper, SAP1 antikoerper, AI037048 antikoerper, SGP-1 antikoerper, SGP1A antikoerper, cb759 antikoerper, wu:fa14a06 antikoerper, wu:fb36e02 antikoerper, wu:fb58g07 antikoerper, PSAP antikoerper, PSP-A antikoerper, SFTPA1B antikoerper, SP-A antikoerper, prosaposin antikoerper, surfactant protein A1 antikoerper, PSAP antikoerper, Psap antikoerper, psap antikoerper, LOC100011417 antikoerper, LOC100304726 antikoerper, LOC100526719 antikoerper, SFTPA1 antikoerper

Hintergrund: This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht: 58.1 kDa

Gen-ID: 5660

UniProt: P07602

Pathways: Positive Regulation of Endopeptidase Activity