SQSTM1 Antikörper (AA 232-356)
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- Target Alle SQSTM1 Antikörper anzeigen
- SQSTM1 (Sequestosome 1 (SQSTM1))
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Bindungsspezifität
- AA 232-356
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser SQSTM1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human SQSTM1 (AA: 232-356) expressed in E. coli.
- Isotyp
- IgG1
- Top Product
- Discover our top product SQSTM1 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.0 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
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- Target
- SQSTM1 (Sequestosome 1 (SQSTM1))
- Andere Bezeichnung
- SQSTM1 (SQSTM1 Produkte)
- Synonyme
- SQSTM1 antikoerper, sqstm1 antikoerper, MGC79491 antikoerper, A170 antikoerper, OSIL antikoerper, PDB3 antikoerper, ZIP3 antikoerper, p60 antikoerper, p62 antikoerper, p62B antikoerper, OSF-6 antikoerper, Osi antikoerper, STAP antikoerper, ZIP antikoerper, sb:cb621 antikoerper, zgc:85784 antikoerper, sequestosome 1 antikoerper, sequestosome 1 L homeolog antikoerper, SQSTM1 antikoerper, sqstm1 antikoerper, Sqstm1 antikoerper, sqstm1.L antikoerper
- Hintergrund
- This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway.The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals.Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene.Mutations in this gene result in sporadic and familial Paget disease of bone.
- Molekulargewicht
- 47.7 kDa
- Pathways
- NF-kappaB Signalweg, Neurotrophin Signalübertragung, Autophagie
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