STAP2 Antikörper (C-Term)

Produktnummer ABIN184610

Produktdetails anti-STAP2 Antikörper

Target: STAP2 (Signal Transducing Adaptor Family Member 2 (STAP2))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser STAP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: STAP2 / BKS

Sequenz: ELQKKLEKRR ALEH

Spezifität: This antibody is expected to recognise isoforms 1 (NP_060190.2) and isoform 2 (NP_001013863.1).

Kreuzreaktivität: Human

Aufreinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Güteklasse: Verified

Immunogen: Peptide with sequence C-ELQKKLEKRRALEH, from the C Terminus of the protein sequence according to NP_060190.2, NP_001013863.1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Western Blot: Approx 48 kDa band observed in Human Heart lysates and 45 kDa band observed in Human Breast Lysates (calculated MW of 49.6 kDa according to NP_060190 and of NP_001013863.1). Recommended concentration: 0.5-1.5 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:128000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Referenzen für anti-STAP2 Antikörper (ABIN184610)

Ikeda, Mizushima, Sekine, Yamamoto, Muromoto, Nanbo, Oritani, Yoshimura, Matsuda: "Involvement of STAP-2 in Brk-mediated phosphorylation and activation of STAT5 in breast cancer cells." in: Cancer science, Vol. 102, Issue 4, pp. 756-61, (2011) (PubMed).

Ikeda, Sekine, Mizushima, Nakasuji, Miyasaka, Yamamoto, Muromoto, Nanbo, Oritani, Yoshimura, Matsuda: "Interactions of STAP-2 with Brk and STAT3 participate in cell growth of human breast cancer cells." in: The Journal of biological chemistry, Vol. 285, Issue 49, pp. 38093-103, (2010) (PubMed).

Ikeda, Miyasaka, Sekine, Mizushima, Muromoto, Nanbo, Yoshimura, Matsuda: "STAP-2 is phosphorylated at tyrosine-250 by Brk and modulates Brk-mediated STAT3 activation." in: Biochemical and biophysical research communications, Vol. 384, Issue 1, pp. 71-5, (2009) (PubMed).

Sekine, Ikeda, Tsuji, Yamamoto, Muromoto, Nanbo, Oritani, Yoshimura, Matsuda: "Signal-transducing adaptor protein-2 regulates stromal cell-derived factor-1 alpha-induced chemotaxis in T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 12, pp. 7966-74, (2009) (PubMed).

Details zu STAP2

Target: STAP2 (Signal Transducing Adaptor Family Member 2 (STAP2))

Andere Bezeichnung: STAP2 (STAP2 Produkte)

Synonyme: BKS antikoerper, AW049765 antikoerper, STAP-2 antikoerper, wu:fa55b07 antikoerper, zgc:77021 antikoerper, cb901 antikoerper, stap2 antikoerper, wu:fd15d07 antikoerper, zgc:63913 antikoerper, signal transducing adaptor family member 2 antikoerper, signal transducing adaptor family member 2b antikoerper, signal transducing adaptor family member 2a antikoerper, STAP2 antikoerper, Stap2 antikoerper, stap2b antikoerper, stap2a antikoerper

Hintergrund: STAP2, BKS, STAP-2, FLJ20234, breast tumor kinase substrate, brk kinase substrate, signal-transducing adaptor protein-2, signal transducing adaptor family member 2

Gen-ID: 55620

NCBI Accession: NP_060190, NP_001013863