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ROCK1 Antikörper
ROCK1
Reaktivität: Human
WB, ELISA
Wirt: Maus
Monoclonal
unconjugated
Produktnummer ABIN1846125
Produktdetails anti-ROCK1 Antikörper
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Target
Alle ROCK1 Antikörper anzeigen
ROCK1
(rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))
Reaktivität
Alle Reaktivitäten für ROCK1 Antikörper
Human
Wirt
Alle Wirte für ROCK1 Antikörper
Maus
Klonalität
Alle Klonalitäten für ROCK1 Antikörper
Monoklonal
Konjugat
Alle Konjugate für ROCK1 Antikörper
Dieser ROCK1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für ROCK1 Antikörper
Western Blotting (WB), ELISA
Aufreinigung
Purified antibody
Immunogen
Purified recombinant fragment of human ROCK1 expressed in E. Coli.
Isotyp
IgG1
Top Product
Discover our top product ROCK1 Primärantikörper
Alternativen
(anzeigen)
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (pSer456), (pThr455) antibody
ROCK1
Reaktivität: Human, Maus, Ratte
WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro)
Wirt: Kaninchen
Polyclonal
unconjugated
Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1.0 mg/mL
Buffer
PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Details zu ROCK1
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Target
ROCK1
(rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))
Andere Bezeichnung
ROCK1 (ROCK1 Produkte )
Synonyme
LOC100229794 antikoerper, CG9774 antikoerper, DROK antikoerper, DRhk antikoerper, DRok antikoerper, Dmel\\CG9774 antikoerper, Drok antikoerper, ROCK antikoerper, ROCK-1 antikoerper, ROCK1 antikoerper, ROK antikoerper, ROKalpha/beta antikoerper, Rhk antikoerper, RhoK antikoerper, Rock antikoerper, Rok antikoerper, dROK antikoerper, dRok antikoerper, drok antikoerper, 1110055K06Rik antikoerper, Rock-I antikoerper, P160Rock antikoerper, ROCK-I antikoerper, P160ROCK antikoerper, p160ROCK antikoerper, Rho associated coiled-coil containing protein kinase 1 antikoerper, Rho kinase antikoerper, Rho-associated coiled-coil containing protein kinase 1 antikoerper, Rho-associated, coiled-coil containing protein kinase 1 antikoerper, ROCK1 antikoerper, Rok antikoerper, Rock1 antikoerper, rock1 antikoerper
Hintergrund
This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity.
Molekulargewicht
158 kDa
Gen-ID
6093
UniProt
Q13464
Pathways
Microtubule Dynamics , WNT Signalweg , M Phase , Maintenance of Protein Location , Signaling Events mediated by VEGFR1 and VEGFR2 , Thromboxane A2 Receptor Signaling
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